Thyroid disease test kit OB175

thyroid stimulating hormonefree T4blood

Thyroxine(T4), along with Triiodothyronine(T3), is one of the two major hormones produced by the thyroid gland and is a diagnostic marker used to determine hyperthyroidism and hypothyroidism. When the concentration of thyroid hormone in the blood increases, the hypothalamus stimulates the pituitary gland through the secretion of Thyrotropin-Releasing Hormone and TRH to synthesize and secrete Thyroid Stimulating Hormone. This secreted TSH stimulates the thyroid gland to synthesize and secrete thyroid hormones T3 and T4. This secreted T4 circulates between T4 bound to blood protein and Free T4 unbound. Most of the T4 found in the blood is bound to proteins, and Total T4 can be affected by the concentration or binding ability of the protein. In contrast, Free T4, which is free from blood, is not affected by proteins. In the case of thyroid hormone, it can not function as a thyroid hormone when it is bound to a protein, so it must be finally changed to Free T3 or Free T4, but may not change due to pregnancy, stress, or hormonal imbalance. On the other hand, Free T4, which is unbound with protein, has the characteristic that it can act directly in the blood. Specification Working range - 0.10-8.00 ng/dL Reference range - 0.8-1.9 ng/dL Sample type - Serum / Plasma Sample volume - 100 μL Loading volume - 100 μL Storage condition - Cartridge: 2-30 ℃ Detection buffer: 2-8 ℃ Shelf life - 24 months