The conic calibrator CPS Developer has been manufactured with the purpose of offering higher calibration versatility, in such a way that a wide variety of materials could be calibrated with the highest accuracy required.
- Deflector baffles.
- Adjustable impeller height.
- Entirely dismantle.
- Vacuum loading accessories.
- According to GMP guidelines.
- FAT - SAT - Validation Documents.
The shape, size and size distribution of the pharmaceutical solids particles, are the three principal factors that can affect primarily the fluency of a mix and so have a bearing on the dosage operations as are the compression and filling of capsules.
They can also affect other unitary pharmaceutical operations as the wet granulation of high shear mixer, since the changes in the size of raw material particles are converted in changes on the surface and the volume of the agglutinating liquid and the end point (torque) of the process are modified.
Also the size of the particle of the actives has a great incidence over the speed dissolution.
Particle size reduction, grinding or calibration, are some of the denominations that are given to an important stage in the manufacture of solid pharmaceutical products which has as an objective: “Reduce and standardize the size and affect the shape of the soild particles of raw material and dry or wet granules”