Formalin reagent IC204

buffer solutionfixative solutionfor histology

Neutral Buffered Formalin 10% is an aqueous formaldehyde-based mixture intended exclusively for professional use in laboratory, diagnostic, and technical settings. The product is supplied by Pro-Eko Srl as a ready-to-use solution, developed for regulated applications that require controlled, stable, and reproducible chemical conditions.
From a chemical perspective, formaldehyde is the simplest of the aldehydes.

• IUPAC Name: methanal
• Chemical Formula: CH2O
• CAS Number: 50-00-0

Neutral Buffered Formalin 10% corresponds to a solution containing 4% formaldehyde, stabilized by a phosphate buffer. The formulation is designed to operate at a neutral pH, according to established criteria in the histological field, and is intended for structured professional contexts to be used by adequately trained personnel.
Product Characteristics – Neutral Buffered Formalin 10% :
Neutral Buffered Formalin 10% provided by Pro-Eko Srl is a chemical fixative widely used in histological and anatomo-pathological fields, thanks to its ability to preserve tissue structure reliably and compatibly with subsequent analytical phases.
The chemical mechanism of fixation is based on the formation of methylene bridges by the active form of formaldehyde (methylene glycol), resulting in intra- and intermolecular cross-linking. These covalent bonds involve numerous functional groups present in biological macromolecules, including amino acid residues and carbohydrate components, contributing to the structural stabilization of the sample.