The whole-body plethysmograph (WBP) developed by Tow-Int is capable of measuring respiratory parameters of animals in the conscious state and under unrestrained conditions, such as respiratory rate, moisture volume, Airway hyperresponsiveness (AHR) test, etc. WBP avoids the trauma of aerosols tube incision and the effects of anesthesia, and the whole experimental process is simpler, specifically suited research on drugs and their reactivities, pharmacology and toxicology studies of respiratory drugs, particularly suitable for a large badge subject for an early rapid screening test, suitable for long-term follow-up research and repeated screening.
Product Features: Unrestrained, Non-invasive, Animal in Conscious State
Ti: Inspiratory Time (s)
Te: Expiratory Time (s)
PIF: Peak Inspiratory Flow (ml/s)
PEF: Peak Expiratory Flow (ml/s)
Volbal：Difference between Inspiratory/Expiratory Volume
F：Flowrate (breaths per minute)
EF50: Mid-tidal Expiratory Flow
EIP：End-inspiratory Pause (Invasive Method)
EEP：End-expiatory Pause (Invasive Method)
TR: Relax Time
Rpef：Ratio of Time to Peak Expiratory Flow
Applications on Respiratory System:
Research on various respiratory diseases, such as asthma, pulmonary fibrosis, lung injury, ARDS, lung cancer, etc.
Safety pharmacology: the effect of drugs
Sleep apnea: monitor animal hypopnea, obstructive apnea, etc.
Environmental Toxicology: The impact of environmental pollutants
Inhalation Toxicology: Toxic effects of toxic substances
High altitude medicine: the influence of high altitude environment