Diagnostic management and analysis system DAPPS

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Product overview
Diagnostic Applications (DAPPS) is a field-of-view-based image analysis platform tailored for rapid, targeted quantification and automated cell counting in diagnostic workflows. Designed for pathologists, it delivers specialized modules for key biomarkers, powerful segmentation algorithms with manual refinement tools, case organization and collaboration features, and on-premise deployment for enhanced data security and control. The software is intended as a decision-support tool for trained professionals and supports analysis of high-resolution digital pathology slides from FFPE tissue specimens and cytology samples.

Key features

• Targeted, field-of-view image analysis focusing on specific tissue areas to provide precise, relevant insights for diagnostics.
• Comprehensive biomarker assessment via specialized modules (Estrogen, Progesterone, HER2, Ki67, GEPNET, PD-L1).
• Automated cell counting for high-throughput, standardized quantification to improve speed, consistency and reproducibility.
• Manual and semi-automatic adjustment tools allowing pathologists to refine segmentation and detection in complex or ambiguous regions.
• Calibration and standardization features with robust sample databases and quality-control protocols to ensure reproducible results.
• Automated case organization showing measurement results, charts and masked images within the pathology workflow to support diagnoses and collaboration.
• Secure on-premise deployment options to keep data locally and comply with privacy regulations.

Key quantification biomarkers

• Ki67 – The Ki67 tool, now IVDR-Certified, measures the proliferation index on a selected region of the slide. (IVDR-Certified)
• Estrogen – Measures the Allred Total Score on a selected region of the slide. (Validated for research purposes)
• Progesterone – Measures the Allred Total Score on a selected region of the slide. (Validated for research purposes)
• HER2 – Measures the Field Score on a selected region of the slide. (Validated for research purposes)
• GEPNET – Measures the GEPNET score on a selected region of the slide. (Validated for research purposes)
• PD-L1 – The MembraneQuant-based Lung PD-L1 tool measures TPS score on a selected region of the slide. (Validated for research purposes)

Installation
Diagnostic Applications is designed to operate optionally within ClinicalViewer and requires ClinicalViewer to be installed prior to setting up the application. It is not a standalone software and functions as a tool for enhanced workflows. No license file or dongle is needed. Accessibility is controlled via CaseManager DX. Regulatory availability may vary by product variant and country.

System requirements

• Monitor / Display resolution: 1280 x 720 or better
• Operating system: Windows 11 (minimum Windows 10 22H2, Professional 64-bit)
• All-in-one PC with virtual server: minimum CPU Intel 3.2 GHz i5 (quad core), 4 GB RAM
• Disk space: Minimum 800 MB (Diagnostic Applications 3.1 – 150 MB; ClinicalViewer 3.0 – 650 MB)

Notes

• Both ClinicalViewer and Diagnostic Applications installer files can be downloaded from the CaseManager DX user interface when available.
• Regulatory disclaimer: Available in specific product variants and may not be available in every country where the company is present.

Caractéristiques / spécifications techniques

• Type: Field-of-view-based image analysis platform for digital pathology
• Primary functions: targeted quantification, automated cell counting, segmentation with manual refinement, case organization
• Specialized modules: Ki67 (IVDR-Certified), Estrogen, Progesterone, HER2, GEPNET, PD-L1 (research-validated variants)
• Deployment: on-premise (local hosting) to enhance data security and regulatory compliance
• Integration: designed to operate within ClinicalViewer and managed via CaseManager DX
• Automation: high-throughput standardized quantification with manual correction options
• Quality control: calibration and standardization tools, sample database support
• Intended users: trained pathology professionals as a decision-support tool
• Notable constraints: not a standalone application; ClinicalViewer required for operation