Microscope slide scanner PANNORAMIC® 250 Flash III DX

with barcode readerhigh-capacityautomatic

Overview
The Pannoramic 250 Flash III DX is a digital whole-slide scanner for brightfield imaging with an optional fluorescence upgrade, intended for medium-volume diagnostic clinics and medical centers. It supports peripheral blood smears, histology and cytopathology workflows and integrates automated slide handling with AI-based tissue detection.

Key Features

• Scanning for peripheral blood smears and histology
• High-resolution brightfield whole-slide imaging
• Cytopathology-optimized modes for cell-level analysis
• Cost-efficient throughput suitable for diagnostic clinics
• AI-driven tissue detection with automated slide management
• Fully automatic slide loading and high-throughput scanning

Capacity & Performance

• Capacity: Up to 300 slides (12 magazines × 25 slides) or continuous loading
• Fully automatic loading and scanning
• Scanning speed: Up to 30 seconds per slide
• Throughput: Up to 60 slides per hour

Imaging & Optics

• Brightfield scanning: Yes
• Flash scanning: Yes
• Illumination: Precision-aligned Pulse Xenon light source
• Image output formats: MRXS or DICOM
• Tissue detection: AI-based, fully automated

Optical Configurations & Options
Customizable configurations and options are available to match diagnostic or research requirements.

• Default objective: 20x/0.8 NA; optional combinations such as 20x/0.8 NA + 40x/0.95 NA
• Supported magnifications (examples): 40x / 80x, 50x / 100x, 55x / 110x
• Number of objectives supported: Up to 2 (dual) — motorized objective changer included when two objectives selected
• Camera options: 21 MP Adimec CMOS (default), 12 MP Adimec CMOS, or 25 MP CIS CMOS
• Additional imaging: Multilayer (Z-stack) and extended focus scanning

Slide & Sample Compatibility

• Compatible slides: Single standard slides (75 mm × 25 mm) and double-width slides
• Coverslip thickness supported: No. 1 or No. 1.5 (0.13–0.19 mm)
• Barcode reading: 1D and 2D

Focus & Scanning Modes

• Focus layering: Single, multi-layer (Z-stack), and extended focus
• Cytopathology-optimized scanning modes for detailed cell imaging

Physical & System Characteristics

• Dimensions (W×D×H): 673 mm × 742 mm × 576 mm
• Weight: 46 kg (base unit)
• Base unit intended for mid-volume clinical deployments balancing throughput and capacity

Optional Research / Fluorescence Upgrade
The unit can be upgraded for research use with a fluorescence illumination engine providing multi-channel FL scanning and advanced options:

• High-performance fluorescence illumination engine (research upgrade)
• 9-tube FL scanning with 9 software-controlled filter positions
• Support for up to 45 logical FL channels (software-controlled)
• Multiband FL filter compatibility
• Slide sensor to detect empty positions within magazines

Use Cases
Intended for biopsy diagnostics, frozen sections, cytopathology, diagnostic immunohistochemistry, diagnostic toxicologic pathology, neuropathology and other diagnostic workflows where whole-slide imaging, automation and AI-assisted tissue detection support diagnostic processes.

Technical specifications

• Model: Pannoramic 250 Flash III DX
• Capacity: Up to 300 slides (12 magazines × 25 slides) or continuous loading
• Scanning speed: Up to 30 sec/slide
• Throughput: Up to 60 slides/hour
• Objectives: Default 20x/0.8 NA; optional dual-objective configurations (motorized changer when two objectives selected)
• Magnification options: e.g. 40x/80x, 50x/100x, 55x/110x (depending on configuration)
• Image sensors: 21 MP Adimec CMOS (default), 12 MP Adimec CMOS, or 25 MP CIS CMOS
• Image output: MRXS or DICOM
• Illumination: Precision-aligned Pulse Xenon light source
• Tissue detection: AI-driven, fully automated
• Focus modes: Single, multi-layer (Z-stack), extended focus
• Slide compatibility: Single standard slides (75×25 mm), double-width slides; coverslip thickness 0.13–0.19 mm
• Barcode: 1D and 2D reading
• Dimensions: 673 mm × 742 mm × 576 mm
• Weight: 46 kg (base unit)
• Optional fluorescence upgrade: 9-tube FL engine, up to 45 logical FL channels, multiband filter support, slide-empty detection