Hemostatic gel TISSEEL

For more than 40 years, TISSEEL fibrin sealant has been trusted worldwide for proven hemostasis and sealing where standard surgical techniques appear insufficient. TISSEEL is the only fibrin sealant indicated for both hemostasis and sealing, and use in heparinized patients. Mimics Physiological Clot TISSEEL contains a unique formulation of fibrinogen and thrombin which, upon mixing, mimics a physiological clot. The aprotinin in TISSEEL increases resistance of the fibrin sealant clot to degradation in a fibrinolytic environment. Selected Risk Information: Do not use TISSEEL in individuals with a known hypersensitivity for aprotinin. Mechanism of Action Upon mixing, human sealer protein and human thrombin combine into fibrin that adheres to the wound surface and achieves hemostasis and sealing. TISSEEL mimics the final coagulation cascade step by forming a clot. Learn more about how TISSEEL works. Additional Product Benefits Wide Range of Applicators TISSEEL is the only fibrin sealant to offer a complete portfolio of drip and spray applicators, allowing surgeons to select the right tools to address individual patient needs. This abbreviated summary of product characteristics (SPC) is intended for international use. Please note that it may differ from the licensed SPC in the country where you are practicing. Therefore, please always consult your country-specific SPC or package leaflet. Fibrin Sealant TISSEEL Lyo – Powders and solvents for sealant TISSEEL – Solutions for sealant COMPOSITION (after mixing), per 1ml Component 1 (Sealer protein solution): Human fibrinogen (as clottable protein) 45.5mg, Aprotinin (synthetic) 1500 KIU