Skin closure surgery tissue adhesive ARTISS

wound closure surgery

Product overview
ARTISS is a fibrin sealant used to adhere autologous skin grafts to surgically prepared burn wound beds in adults and pediatric patients ≥ 1 year. ARTISS is also indicated for adhesion of tissue flaps during facial rhytidectomy (face‑lift) procedures. The product is supplied as a human fibrin sealant in pre-filled syringes and is available in frozen presentations for certain SKUs.

Packaging & general contents

• Each package typically contains 1 pre-filled syringe of ARTISS and the ARTISS Package Insert.
• Selected codes include the TISSEEL/ARTISS SPRAY SET (for use with the EASYSPRAY Pressure Regulator).
• Frozen variants are supplied in double-pouched packaging for cold-chain handling.
• Available sizes: examples include 2 mL, 4 mL and 10 mL presentations.

Available product variants (examples shown on page)

• ARTISS, PRE-FILLED 2 mL — Item #: 5500694 — 1 pre-filled syringe; frozen presentation in a double-pouched package.
• ARTISS, PRE-FILLED 4 mL — Item #: 5500695 — 1 pre-filled syringe; frozen presentation in a double-pouched package.
• ARTISS, PRE-FILLED 10 mL — Item #: 5500696 — 1 pre-filled syringe; frozen presentation in a double-pouched package.
• ARTISS (Frozen) Pre-Filled 2 mL Syringe with Spray Set — Item #: 5500694SP — includes ARTISS Package Insert and TISSEEL/ARTISS SPRAY SET.
• ARTISS (Frozen) Pre-Filled 4 mL Syringe with Spray Set — Item #: 5500695SP — includes ARTISS Package Insert and TISSEEL/ARTISS SPRAY SET.
• ARTISS (Frozen) Pre-Filled 10 mL Syringe with Spray Set — Item #: 5500696SP — includes ARTISS Package Insert and TISSEEL/ARTISS SPRAY SET.

Compatible accessories & related products

• COSEAL Surgical Sealant Spray Set for EASYSPRAY — disposable sterile spray set for gas activation; for open procedures. List price indicated on page: $761.65.
• EASYSPRAY Pressure Regulator — device to control and release pressurized gas for spray activation; includes regulator, manual and 9V battery.
• EASYSPRAY Set with EASYSPRAY Pressure Regulator — disposable spray set (spray head, dual-lumen tube with filters and clip) used with double syringe systems; topical use only; available in cases of 10. List price indicated on page for set with regulator: $691.22.

Clinical indications & use

• Adhesion of autologous skin grafts to surgically prepared burn wound beds in adults and pediatric patients aged ≥ 1 year.
• Adhesion of tissue flaps during facial rhytidectomy (face‑lift) surgery.

Notes

• Packaging presentation and accessory compatibility (spray sets, pressure regulator) vary by SKU; consult the specific item listing for details.
• Frozen presentation requires appropriate cold-chain handling; some SKUs are supplied frozen in double-pouched packaging.

Characteristics / technical specifications

• Commercial name (model): ARTISS
• Indication: fibrin sealant for adhesion of autologous skin grafts and tissue flaps during facial rhytidectomy
• Patient population: adults and pediatric patients ≥ 1 year
• Presentation: pre-filled syringe (examples: 2 mL, 4 mL, 10 mL); frozen double-pouched packaging for certain SKUs
• Package contents: typically 1 pre-filled syringe + ARTISS Package Insert; selected SKUs include TISSEEL/ARTISS SPRAY SET
• Spray compatibility: TISSEEL/ARTISS SPRAY SET compatible with EASYSPRAY Pressure Regulator / EASYSPRAY system
• Example item numbers: 5500694, 5500695, 5500696, 5500694SP, 5500695SP, 5500696SP
• Related accessories: COSEAL Surgical Sealant Spray Set for EASYSPRAY; EASYSPRAY Pressure Regulator; EASYSPRAY Set with Pressure Regulator