Xenograft bone substitute Bone Pastes

for orthopedic surgerymalleable

Bone Pastes Bioteck bone pastes are obtained from equine bone tissue through an exclusive physicochemical process of enzymatic deantigenation and subsequently of total demineralization of bone matrix. Using digestive enzymes, which work at physiological temperature (37°C), makes it possible to completely remove the tissue antigenic component without changing the native conformation of collagenous matrix molecules, which is therefore totally preserved. The deantigenated tissue is subjected to a total demineralization process. Calcium salts are completely hydrolised in acid medium, by applying at the same time a difference of electrical potential to foster the ionic migration in solution. Therefore, the collagenous matrix, having on its surface specific molecular signals that foster regeneration, is completely exposed and is able to exert a positive effect of osteopromotion. In its native conformation, bone collagen exerts all its own effects: the function of coactivator of endogenous growth factors and the function of scaffold for osteoblast cell adhesion, thus creating an environment which is physiologically and biologically favourable for bone regeneration.