Containment isolator HPTCI

dispensingfor active pharmaceutical ingredientsfor mills

Overview Envair Technology's High Potent Turbulent Containment Isolator (HPTCI) is a rigid isolator engineered to provide operator protection and containment for handling highly potent active pharmaceutical ingredients (HPAPIs) and oral solid dose (OSD) processes such as weighing, dispensing, milling and potent compounding. The HPTCI is designed for manufacturing environments requiring containment performance up to OEB5–OEB6.

Design and construction Customisable chamber layouts and ergonomic design to fit specific workflows. Each chamber can be supplied with an independent exhaust fan and filter assembly. Inflatable silicone primary seals are fitted on the main chamber and hatch doors to ensure reliable sealing integrity and repeatable performance.

Filtration and airflow The isolator uses safe-change HEPA filtration and independent exhaust for each chamber to maintain containment and minimise cross-contamination risk. Airflow patterns are engineered to support turbulent containment for potent powders and solids.

Applications

• Weighing and dispensing of potent powders and APIs
• Milling and size-reduction operations involving potent materials
• Potent compounding and formulation of HPAPIs

Key Features

• Containment performance rated to OEB5–OEB6
• Automatic inflatable silicone primary seals on main chamber and hatch doors
• Safe-change HEPA filter system (operator-changeable)
• Independent exhaust fan and filter assembly per chamber
• Customisable chamber layouts and internal configuration

Technical specifications

• Containment: up to OEB5–OEB6
• Primary sealing: automatic/inflating silicone seals on main chamber and hatches
• Filtration: safe-change HEPA filters, operator-changeable
• Exhaust: independent fans and filter assemblies per chamber
• Configuration: bespoke chamber layouts to suit process requirements
• Typical uses: weighing, dispensing, milling, potent compounding of HPAPIs