Weighing area isolator

for highly potent active pharmaceutical ingredientsfor small-scale productiondispensing

Product overview
This negative‑pressure rigid isolator is designed for R&D and small‑scale laboratories that need safe weighing and dispensing of Highly Potent Active Pharmaceutical Ingredients (HPAPIs) and hazardous powders.

Performance
Provides OEB5 containment performance with validated containment to <0.01 μg/m³, a safe‑change primary exhaust filter and an automated pressure decay leak test for repeatable verification and trend monitoring.

Design and operation
Available in two‑glove and four‑glove configurations, with selectable working area widths and options for additional exhaust fans and filters. The isolator features transfer chambers with timed electromagnetic interlocks and is controlled via PLC for simplified setup, operation and maintenance.

Key features

• Negative pressure operation for operator protection
• Validated containment to <0.01 μg/m³ (OEB5)
• Safe‑change primary exhaust filter
• Automated pressure decay leak test with trend indication
• Transfer chambers with electromagnetic timed interlocks and high air‑change rates to prevent airborne contamination during transfers and to speed disinfectant evaporation
• PLC controls for straightforward setup, operation and maintenance
• Good access to potentially contaminated areas to facilitate cleaning
• EU GMP Grade A unidirectional airflow work area for aseptic/product protection
• Available ducted and recirculating models; two‑glove and four‑glove variants

Applications
Intended for safe handling, weighing and dispensing of hazardous powders and HPAPIs in R&D, formulation development and small‑scale production where high containment is required.

Specifications

• Containment level: OEB5
• Validated containment limit: <0.01 μg/m³
• Operating mode: Negative pressure for operator protection
• Filtration: Safe‑change primary exhaust filter; options for additional exhaust fans and filters
• Leak testing: Automated pressure decay leak test with trend monitoring
• Transfer system: Transfer chambers with electromagnetic timed interlocks and high air‑change rates
• Control system: PLC controls for setup, operation and maintenance
• Work area airflow: EU GMP Grade A unidirectional airflow for aseptic/product protection
• Configuration options: Two‑glove or four‑glove variants; ducted and recirculating models; selectable working area widths
• Cleaning/maintenance: Good access to potentially contaminated areas to facilitate cleaning