OverviewThe Franz Cell measures cumulative permeation and absorption rates of active compounds across membranes to predict transdermal drug kinetics. It is designed for laboratory transdermal and topical penetration testing in pharmaceutical and biomedical research.
IntroductionDesigned for vertical transdermal experiments, the Franz Cell is suitable for testing penetration of solids and semi-solids (e.g., ointments, patches) through human or animal skin, skin models, cornea and other membranes. It supports routine in vitro release and permeation studies with controlled stirring and temperature.
Key features- Precise temperature control: accuracy 0.2℃, adjustable from room temperature up to 70℃.
- Independent stirring and timing: rotation speed 0–999 rpm with programmable stop time.
- Multi‑size receiver cells: available volumes include 2.2 mL, 8 mL and 20 mL; custom sizes supported; specialized cornea and nail cells offered.
- Durable construction: main body and internal components in stainless steel; separate control of heating and stirring for stable operation.
Technical specifications- Number of channels: 12
- Speed control accuracy: 1 rpm
- Speed consistency per channel: ≤0.5%
- Rotation modes: forward and reverse
- Temperature control accuracy: 0.2℃
- Receiver cell volumes (examples): 2 mL, 5 mL, 7.8–8 mL, 18 mL (customizable)
Available transdermal cells (examples)Model | Volume | Transdermal area (cm²) | Typical loading
TR-0010 | 2 mL | 0.79 cm² | Low
TR-0025 | 7.8 mL | 1.91 cm² | Medium
TR-0030 | 8 mL | 3.24 cm² | Medium
TR-0035 | 18 mL | 4.14 cm² | High
TR-0115 | 5.4 mL | 0.57 cm² | Cornea
TR-0116 | 5 mL | 0.79 cm² | Nail
TR-0010-X | Vertical type; receiver volume, aperture and area per custom specification
TR-0115-X | Corneal type; receiver volume, aperture and area per custom specification
Customization & orderingCustom receiver volumes, apertures and transdermal areas available on request. Contact sales for specialized corneal or nail cell configuration, channel count variations and laboratory integration options.