Enzyme reagent kit C005 series

for mutation detectionliquidprotein

The Magigen CRISPR Cas13a protein (CRISPR associated protein 13a, C2c2) is part of the Type VI CRISPR-Cas system. It has RNA-guided RNA cleavage activity. It is the only protein that can degrade RNA found in the second largest class of CRISPR-Cas systems by now. Introduction The Cas13a can be used for RNA gene editing and RNA detection in vitro, achiving superior sensitivty for detecting DNA genotypes and RNA pathogens; including viruses, bacteria, resistance genes and cancer mutations. When using the Cas13a, methods like RPA, LAMP and PCR are all apply to it. Unit Definition ♦ This product is a recombinant protein ♦ This product 1pmol=144 ng. Product Features The design and stabilization of sgRNAs have a great influence on the reaction system, and whether sgRNAs can be degraded by gel electrophoresis before the reaction is carried out. Product Performances By cutting RNA with different concentrations of the Magigen Cas13a protein, it can be found that sufficient amounts of Cas13a able to cleave RNA in less than 10 minutes.