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Solution reagent C006 series
for molecular biologyproteinCRISPR-Cas12b

Solution reagent - C006 series - Guangzhou Magigen Biotechnology Co. Ltd - for molecular biology / protein / CRISPR-Cas12b
Solution reagent - C006 series - Guangzhou Magigen Biotechnology Co. Ltd - for molecular biology / protein / CRISPR-Cas12b
Solution reagent - C006 series - Guangzhou Magigen Biotechnology Co. Ltd - for molecular biology / protein / CRISPR-Cas12b - image - 2
Solution reagent - C006 series - Guangzhou Magigen Biotechnology Co. Ltd - for molecular biology / protein / CRISPR-Cas12b - image - 3
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Characteristics

Type
solution
Applications
for molecular biology
Tested parameter
protein
Other characteristics
CRISPR-Cas12b
Storage temperature

-20 °C
(-4 °F)

Description

Magigen CRISPR Cas12b can be used to detect DNA templates and amplify signals by designing ssDNA probes labeled with fluorescent groups or other markers at both ends. Common detection methods include real-time fluorescence and colloidal gold chromatography. The Cas12b also react more active in envirnment that has higher tempeture (45 ~ 65℃). Hence, this system has been widely used in gene editing of micro organisms, plants and animals, and has great practical application value in molecular diagnosis. Introduction Magigen AapCas12b protein, derived from Alicyclobacillus acidiphilus, is an RNA-mediated endonuclease that binds to and cleaves specific sites of target DNA under the guidance of single-stranded RNA. While Cas12b recognizes and cleaves target double-stranded DNA under the guidance of guide RNA, its collateral cleavage activity is activated, which can efficiently cleave non-specific single-stranded DNA (ssDNA). CRISPR/Cas12b can be used to detect DNA templates and amplify signals by designing ssDNA probes labeled with fluorescent groups or other markers at both ends. Unit Definition ♦ This product is a recombinant protein ♦ This product 1pmol=132 ng. ♦ The design and stabilization of sgRNAs have a great influence on the reaction system, and whether sgRNAs can be degraded by gel electrophoresis before the reaction is carried out. Product Features Cas12b designed to be using in molecular detection for detecting DNA. If the dectecting target RNA needs to combine the DNA enzyme originated from itself, methods like RPA, LAMP and PCR are applying to Cas12b as well.
*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.