Rapid infectious disease test SaberVet

veterinaryvirusinfluenza A

The SaberVet Avian Influenza Virus Antigen Rapid Test sold by Antigenne is a lateral flow immunoassay intended for the qualitative detection of specific antigen from Avian Influenza Virus(AIV) in laryngeal secretions/cloaca swab sample. The test is useful for determination of AIV infection. It is recommended to use in birds with anorexia, cough, sneezing, sinusitis and other symptoms. Description Introduction to Pathology Transmission and Infection Avian Influenza Virus (AIV) belongs to the Orthomyxoviridae family of influenza A viruses. Depending on their surface antigens Hemagglutinin (HA) and Neuraminidase (NA), AIV viruses are classified into several subtypes, of which the H5 and H7 subtypes of highly pathogenic avian influenza (HPAI) are a major threat to avian and human health. Pathologic process Highly pathogenic avian influenza (HPAI): commonly found in the H5 and H7 subtypes, the infection manifests itself as a severe systemic disease with acute onset and high mortality. Pathologic changes include: Acute systemic infection: rapid spread of the virus throughout the body, affecting multiple organs and systems. Tissue lesions: hemorrhage, necrosis, and inflammation, especially in the respiratory and digestive tracts and the nervous system. Immune response: intense inflammatory response and cytokine storm. Low Pathogenic Avian Influenza (LPAI): common in other subtypes, symptoms are mild and usually limited to the respiratory and digestive tracts. Clinical signs Poultry: HPAI: acute death, respiratory distress, decreased egg production, swelling, hemorrhage (infarct spots), diarrhea, neurological signs (e.g., tremors, ataxia).