Rapid infectious disease test SaberVet

veterinaryproteinvirus

Sabervet Avian Influenza Virus H7 Antigen Rapid Test Sold by Antigenne is a lateral flow immunoassay intended for the qualitative detection of specific antigen from Avian Influenza Virus H7 (AIV H7) in laryngeal secretions/cloaca swab sample. The test is useful for determination of AIV H7 infection. Description The H7 antigen in Avian Influenza Virus (AIV) is another important serotype, especially subtypes such as H7N9, which significantly affects both poultry and humans. Characteristics and antigenicity Characteristics Genomic structure: The H7 antigen belongs to the Influenza A Virus, whose genome consists of eight single-stranded negative-stranded RNA segments, each encoding one or more proteins. The H7 antigen mainly involves the Hemagglutinin (HA) protein, which is responsible for viral adhesion and entry into host cells. Hemagglutinin protein: The HA protein is a glycoprotein on the surface of the virus and is classified into 16 serotypes (H1-H16), of which H7 is one. HA proteins are responsible for binding to receptors on the surface of host cells and mediate viral entry into the cell. Antigenic variation: Avian influenza viruses are susceptible to antigenic drift and antigenic switching, leading to the emergence of new subtypes and epidemics. H7N9 is one of the most representative and pathogenic H7 subtypes. Immunogenicity: H7 antigens are highly immunogenic and can induce the host to produce neutralising antibodies against HA proteins. Neutralising antibodies prevent the virus from entering host cells, thus providing immune protection.