Rapid infectious disease test SaberVet

veterinaryproteinvirus

Sabervet Avian Influenza Virus H9 Antigen Rapid Test sold by Antigenne is a lateral flow immunoassay intended for the qualitative detection of specific antigen from Avian Influenza Virus H9 (AIV H9) in laryngeal secretions/cloaca swab sample. The test is useful for determination of AIV H9 infection. Description The H9 antigen in Avian Influenza Virus (AIV) is another important serotype, especially the H9N2 subtype, which has a significant impact on poultry and is also a potential threat to humans. Characteristics and antigenicity Characteristics Genomic structure: The H9 antigen belongs to the Influenza A Virus, whose genome consists of eight single-stranded negative-stranded RNA segments, each encoding one or more proteins. The H9 antigen mainly involves the Hemagglutinin (HA) protein, which is responsible for viral adhesion and entry into host cells. Hemagglutinin protein: The HA protein is a glycoprotein on the surface of the virus and is classified into 16 serotypes (H1-H16), of which H9 is one. HA proteins are responsible for binding to receptors on the surface of host cells and mediate viral entry into the cell. Antigenic Mutation: Avian influenza viruses are prone to antigenic drift and antigenic switching, leading to the emergence and prevalence of new subtypes.H9N2 is one of the most representative and widespread H9 subtypes. Immunogenicity: H9 antigens are highly immunogenic and can induce the host to produce neutralising antibodies against HA proteins. Neutralising antibodies prevent the virus from entering host cells, thus providing immune protection.