Rapid infectious disease test SaberVet

veterinaryproteinvirus

SaberVet Avian Influenza Virus H5 Antigen Rapid Test Sold by Antigenne is a lateral flow immunoassay intended for the qualitative detection of specific antigen from Avian Influenza Virus H5 (AIV H5) in laryngeal secretions/cloaca swab sample. The test is useful for determination of AIV H5 infection. Description Avian Influenza Virus (AIV) is a highly mutable virus belonging to the genus Influenza A virus of the family Orthomyxoviridae.The H5 antigen is an important serotype of avian influenza viruses, especially subtypes such as H5N1 and H5N6, which are of great concern because of their high pathogenicity in poultry and humans. Characteristics and antigenicity Characteristics Genomic structure: Avian influenza viruses are RNA viruses whose genome consists of eight single-stranded negative-stranded RNA segments, each encoding one or more proteins. The H5 antigen mainly involves the Hemagglutinin (HA) protein, which is responsible for viral adhesion and entry into host cells. Hemagglutinin: The HA protein is a glycoprotein on the surface of the virus and is classified into 16 serotypes (H1-H16), of which H5 is one. The HA protein is responsible for binding to a receptor on the surface of the host cell that mediates the entry of the virus into the cell. Antigenic variation: Avian influenza viruses are prone to antigenic drift and antigenic switching, leading to the emergence of new subtypes and epidemics. of the H5 subtypes, H5N1 is one of the most representative and pathogenic. Antigenicity Immunogenicity: The H5 antigen is highly immunogenic and induces the production of neutralising antibodies against the HA protein.