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Research reagent kit AmpliSeq™ BRCA
NGSfor DNA sequencingfor PCR

research reagent kit
research reagent kit
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Characteristics

Applications
for research, NGS, for DNA sequencing, for PCR, FFPE tissues
Tested parameter
for genes

Description

Product Highlights The AmpliSeq for Illumina BRCA Panel is a targeted resequencing assay for research of somatic and germline variants across BRCA1 and BRCA2 genes. Key features include: Relevant Gene Content Target all exonic regions and flanking intronic sequences of BRCA1 and BRCA2 Fast, Streamlined Workflow Prepare sequencing-ready libraries in a single day from as little as 1 ng of high quality or 10 ng of formalin-fixed, paraffin-embedded (FFPE) input samples Accurate Data Detect somatic mutations as low as 5% variant allele frequency using local or cloud based analysis The BRCA Panel is part of an integrated workflow that includes AmpliSeq for Illumina polymerase chain reaction (PCR)-based library preparation, Illumina sequencing by synthesis (SBS) next-generation sequencing (NGS) technology, and automated analysis. BRCA1 and BRCA2 are human tumor suppressor genes that, when carrying specific mutations, have been implicated in an increased risk for breast and ovarian cancers. This ready-to-use panel saves researchers the time and effort of identifying targets, designing primers, and optimizing panels.

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