Freeze dryer for the pharmaceutical industry LYOMAX Series

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Overview
IMA Life LYOMAX is a configurable series of industrial pharmaceutical lyophilizers (freeze dryers) designed for R&D and production of sterile, lyophilised injectables. The range supports stringent process control, fast cycle development and compliance with global regulations (GAMP, cGMP, FDA). Options include HFC or LN2 refrigeration, multiple condenser arrangements and automated loading systems.

Machine highlights

• Machine sizes: vial pack area from 1 to 100 m2 across LYOMAX 1 → LYOMAX 40.
• Configurations: integral or external condenser, two‑storey and pass‑through designs; bespoke engineering available.
• Refrigeration: two‑stage reciprocating semi‑hermetic or screw compressors (Bitzer, Mycom); optional LN2 systems.
• Cooling capability: shelf cooling typically down to −55 / −70 °C; condenser cooling down to −75 / −120 °C depending on refrigerant and configuration.
• Loading/unloading: integrated manual, semi‑automatic or fully automatic systems.
• Vacuum control: capacitance manometers for accurate vacuum measurement and control.
• Nucleation control: KRYOSEQ® sterile LN2 system for controlled, standardized nucleation.

Shelves
FUSION™ / FUSION PLUS™ shelf technology: patented lightweight shelves engineered for improved heat transfer and process reliability compared with conventional designs.

Technical data (model examples)

• LYOMAX 1 — Shelves: 5; Vial pack area (manual): 1.4 m2 (455 × 615 mm); Auto loading: N/A; Condenser capacity: 28 kg @12.7 mm ice; Compressors: 2 × 5 Hp Bitzer; LN2: LF25/12; KRYOAIR: 1 × 23T-0.
• LYOMAX 3 — Shelves: 5; Vial pack area (manual): 2.8 m2 (615 × 916 mm); Auto: 2.6 m2 (615 × 837 mm); Condenser: 70 kg; Compressors: 2 × 8 Hp Bitzer; LN2: LF25/12; KRYOAIR: 1 × 23T-0.
• LYOMAX 5 — Shelves: 6; Vial pack area (manual): 5.0 m2 (916 × 916 mm); Auto: 4.6 m2 (916 × 837 mm); Condenser: 97 kg; Compressors: 2 × 12 Hp Bitzer; LN2: LF25/12; KRYOAIR: 1 × 23T-1.
• LYOMAX 7 — Shelves: 7; Vial pack area (manual): 7.8 m2 (916 × 1,220 mm); Auto: 7.3 m2 (916 × 1,141 mm); Condenser: 143 kg; Compressors: 2 × 16 Hp Bitzer; LN2: LF50/20; KRYOAIR: 1 × 23T-1.
• LYOMAX 10 — Shelves: 9; Vial pack area (manual): 10.0 m2 (916 × 1,220 mm); Auto: 9.4 m2 (916 × 1,141 mm); Condenser: 194 kg; Compressors: 2 × 20 Hp Bitzer; LN2: LF50/20; KRYOAIR: 1 × 23T-1.
• LYOMAX 15 — Shelves: 10; Vial pack area (manual): 14.5 m2 (1,220 × 1,220 mm); Auto: 13.9 m2 (1,220 × 1,141 mm); Condenser: 273 kg; Compressors: 2 × 30 Hp Mycom; LN2: LF50/20; KRYOAIR: 2 × 23T-1.
• LYOMAX 20 — Shelves: 11; Vial pack area (manual): 20.5 m2 (1,220 × 1,524 mm); Auto: 19.4 m2 (1,220 × 1,445 mm); Condenser: 375 kg; Compressors: 2 × 30 Hp Mycom; LN2: LF50/20; KRYOAIR: 1 × 80T-0.
• LYOMAX 25 — Shelves: 14; Vial pack area (manual): 26.0 m2 (1,220 × 1,524 mm); Auto: 24.6 m2 (1,220 × 1,445 mm); Condenser: 476 kg; Compressors: 2 × 50 Hp Mycom; LN2: LF100/50; KRYOAIR: 1 × 80T-1.
• LYOMAX 30 — Shelves: 13; Vial pack area (manual): 30.2 m2 (1,524 × 1,524 mm); Auto: 28.6 m2 (1,524 × 1,445 mm); Condenser: 552 kg; Compressors: 2 × 50 Hp Mycom; LN2: LF100/50; KRYOAIR: 1 × 80T-1.
• LYOMAX 35 — Shelves: 13; Vial pack area (manual): 36.3 m2 (1,524 × 1,830 mm); Auto: 34.7 m2 (1,524 × 1,751 mm); Condenser: 635 kg; Compressors: 2 × 50 Hp Mycom; LN2: LF100/50; KRYOAIR: 1 × 80T-1.
• LYOMAX 40 — Shelves: 15; Vial pack area (manual): 41.8 m2 (1,524 × 1,830 mm); Auto: 40.0 m2 (1,524 × 1,751 mm); Condenser: 731 kg; Compressors: 2 × 50 Hp Mycom; LN2: LF100/50; KRYOAIR: 2 × 80T-0.

Notes & compliance
Configurable from small R&D units to large production plants. Refrigeration may use HFC compressors or LN2; designed for sterile pharmaceutical applications and aligned with GAMP, cGMP and FDA guidance.

Technical specifications

• Machine range: 1–100 m2 vial pack area; multiple LYOMAX models.
• Refrigeration options: semi‑hermetic/screw compressors (Bitzer, Mycom) or LN2 systems.
• Cooling ranges: shelf to approx. −55/−70 °C; condenser to approx. −75/−120 °C depending on configuration.
• Condenser capacity: model dependent (≈28–731 kg @12.7 mm ice).
• Shelf tech: FUSION™ / FUSION PLUS™ for improved heat transfer.
• Nucleation: KRYOSEQ® sterile LN2 for controlled nucleation.
• Vacuum control: capacitance manometers.
• Loading: manual, semi‑automatic or automatic integrated systems.
• Regulatory design: suitable for GMP environments and global licensing requirements.