Biological freeze dryer LYOFAST series

for the pharmaceutical industryfor productionpilot

Overview
Industrial freeze-drying solution for pharmaceutical and biotech production. The LYOFAST series comprises pre-engineered industrial freeze dryers for bulk product or liquid in vials, ampoules or trays, suited to high-value products including vaccines, antibiotics, biologicals, hormones and other active ingredients.

Key features

• Shelf area range: models for pilot to large-scale production, from ~1 m² up to 40+ m².
• Chamber & condenser configurations: cylindrical and rectangular chamber geometries; integral or separate condenser options to fit plant layout.
• Refrigeration options: two-stage semi-hermetic reciprocating compressors, screw compressors, or liquid nitrogen (LN2) cooling.
• Condenser types: direct expansion or fluid-circulation condensers with capacities from ~32 kg to 731 kg @12.7 mm ice (model-dependent).
• Induced nucleation: compatible with KRYOSEQ® for controlled nucleation.
• Shelf technology: FUSION™ brazed shelves and FUSION PLUS™ with non-stick coating for improved heat transfer and durability.
• Process control: advanced control systems and instrumentation with high redundancy for precise process management and product quality.
• Applications: engineered for complex drug formulations, high-potent compounds and processes involving flammable solvents.

Highlights
Modular construction shortens project schedules and reduces lead times; modular approach enables lower cost and faster delivery for large-capacity installations.

Machine media & gallery
Multiple photographic views and a machine video are available showing external and internal views, shelf/vial arrangements, loading details and condenser components.

Technical models (excerpt)

• LYOFAST 1 — Cylindrical integral chamber; up to 5 shelves; manual vial area ~1.4 m² (455 x 615 mm); condenser capacity ~32 kg; compressor example: 2 x 5Hp Bitzer; LN2 option: LF25/12; KRYOAIR: 1 x 23T-0.
• LYOFAST 3 — Cylindrical integral; up to 5 shelves; manual vial area ~2.8 m² (615 x 916 mm); condenser ~67 kg; compressor: 2 x 8Hp Bitzer; LN2: LF25/12; KRYOAIR: 1 x 23T-0.
• LYOFAST 5 — Cylindrical integral; up to 9 shelves; manual vial area ~5.1 m² (615 x 916 mm); condenser ~103 kg; compressors: 2 x 16Hp Bitzer or 2 x 30Hp Mycom; LN2: LF25/12; KRYOAIR: 1 x 23T-1.
• LYOFAST 7 — Cylindrical integral; up to 7 shelves; manual vial area ~7.8 m² (916 x 1,220 mm); condenser ~148 kg; compressors: options up to 2 x 30Hp Mycom; LN2: LF50/20; KRYOAIR: 1 x 23T-1.
• LYOFAST 10 / 15 — Rectangular integral variants; shelf counts and vial areas vary (examples: manual up to ~16–18 m², auto up to ~9.7–17.9 m²); condenser capacities ~186–273 kg; compressor configurations include multiple Bitzer/Mycom units; LN2: LF50/20.
• LYOFAST 20–40 — Large sizes (rectangular or cylindrical); manual shelf area up to ~47.4 m²; auto area up to ~40 m²; condenser capacities ~378–731 kg; multiple compressor configurations (3–4 x 30Hp and larger); LN2: LF100/50 or multiples; KRYOAIR: 1–2 x 80T units depending on model.

Minimum temperatures
Minimum shelf temperature down to approximately -55 °C to -65 °C depending on configuration and oil type. Minimum condenser temperature down to approximately -75 °C to -100 °C depending on configuration.

Technical specifications

• Product family: LYOFAST series (industrial freeze dryers for pharmaceutical/biotech).
• Supported formats: bulk, vials, ampoules, trays.
• Shelf area range: ~1 m² to 40+ m² (model-dependent).
• Chamber geometries: cylindrical integral, rectangular integral (multiple layouts).
• Condenser types & capacity: direct expansion or fluid circulation; ~32–731 kg @12.7 mm ice.
• Refrigeration: two-stage semi-hermetic reciprocating, screw compressors, or LN2 configurations.
• LN2 options: LF25/12, LF50/20, LF100/50 (model-dependent).
• KRYOSEQ / KRYOAIR compatibility: induced nucleation and air/auxiliary configurations available.
• Shelf tech: FUSION™ and FUSION PLUS™ braided/brazed shelves with non-stick coatings.
• Control & instrumentation: advanced control system with redundancy for process control and product quality.
• Modular design: standard modules to compress schedules and reduce lead times for large-capacity equipment.