Freeze dryer for the pharmaceutical industry LYOFAST MINI Series

for research and developmentpilotlow-output

Overview
The LYOFAST MINI range of freeze dryers is a compact, GMP-compliant solution for small-batch production, clinical trials, product development and process cycle optimisation. It is designed for high-value products and personalised medicines and supports early scale-up batches to test process robustness and reduce downstream production costs.

Highlights

• Configurations: Four different configurations available, from 1 to 2.8 m2.
• CIP/SIP: Automatic CIP/SIP included.
• Slot door: Slot door suitable for RABS/isolator integration.
• Applications: Suitable for high-potent products and non-aqueous solvents.
• Temperature probes: Redundant shelf inlet temperature probes and pressure sensors.
• SCADA system: LYOMASTER compact SCADA and high-redundancy control system for optimal process control and enhanced final product quality.
• Induced nucleation: Ready to be integrated with KRYOSEQ® for nucleation control.

FUSION™ shelves
LYOFAST MINI shelves use IMA Life’s patented FUSION™ / FUSION PLUS™ technology: lighter and more resistant than conventional shelves with enhanced heat transfer properties to improve process reliability and product quality.

Integration
Designed for easy integration with UAF, RABS, isolators and automatic/semi-automatic loading and unloading systems.

Technical data (table)
Model | Number of shelves up to | Vial pack area (manual loading) (m2) | Vial pack (wxd) manual loading (mm) | Vial pack area (auto loading) (m2) | Vial pack (wxd) auto loading (mm) | Condenser capacity (kg @12.7 mm ice) | Compressor config. | LN2 config. | KRYOAIR config.
LYOFAST MINI 1 | 3 | 1.1 | 615 x 615 | 1 | 613 x 536 | 28 | 2 x 5Hp Bitzer | LF25/12 | 1 x 23T-0
LYOFAST MINI 1.5 | 4/3 | 1.5 / 1.1 | 615 x 615 | 1.3 / 1 | 613 x 536 | 28 | 2 x 5Hp Bitzer | LF25/12 | 1 x 23T-0
LYOFAST MINI 2.2 | 4 | 2.3 | 615 x 930 | 2.1 | 613 x 837 | 58 | 2 x 8Hp Bitzer | LF25/12 | 1 x 23T-0
LYOFAST MINI 2.8 | 5/4 | 2.9 / 2.3 | 615 x 930 | 2.6 / 2.1 | 613 x 837 | 58 | 2 x 8Hp Bitzer | LF25/12 | 1 x 23T-0
Minimum shelf temperature (5cst/1/6cst oil) | -55C / -60C | -65C | -60C
Minimum condenser temperature | -75C | -100C | -75C

Technical features / specifications

• Models available: LYOFAST MINI 1, LYOFAST MINI 1.5, LYOFAST MINI 2.2, LYOFAST MINI 2.8.
• Number of shelves: from 3 up to 5 (depends on configuration).
• Vial pack area (manual loading): up to 2.9 m2 (varies by model); typical manual-loading pack widths: 615 x 615 mm or 615 x 930 mm.
• Vial pack area (auto loading): up to 2.6 m2; typical auto-loading pack sizes: 613 x 536 mm or 613 x 837 mm.
• Condenser capacity: 28 kg or 58 kg (@12.7 mm ice) depending on model.
• Compressor configuration: 2 x 5Hp Bitzer (smaller models) or 2 x 8Hp Bitzer (larger models).
• Minimum shelf temperature: typically -55°C / -60°C (oil-dependent) down to -65°C for some configs.
• Minimum condenser temperature: down to -75°C (some configs to -100°C).
• Control and automation: LYOMASTER compact SCADA with high redundancy.
• Process features: automatic CIP/SIP, redundant temperature and pressure sensors, KRYOSEQ® integration-ready for induced nucleation control.
• Design for containment: slot door option for RABS/isolator integration; suitable for high-potent products and non-aqueous solvents.