Sliding microtome cryostat CM1950

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The Leica CM1950 is a clinical cryostat engineered for efficient frozen section workflows. It integrates the DualEcoTec cooling system to accelerate cool-down, stabilise chamber temperature and reduce energy consumption. The instrument includes a spacious cryocabinet and integrated quick-freeze stations to facilitate specimen handling, storage and mounting preparation.

Key features

• DualEcoTec cooling: enhanced instrument cooling for faster cool down and improved temperature stability of the cryochamber and specimen.
• Fast freezing: specimen discs with deep-groove design and two integrated Peltier quick-freeze stations to accelerate freeze-down and stabilise mounting.
• Stable cool air circulation: DualEcoTec combined with CryoZone technology forms a stable cool air zone around specimen, blade and anti-roll guide to maintain temperature-critical components during extended sessions.
• Reproducible section quality: CE blade holder accepts high- and low-profile disposable blades and allows lateral movement; optional CNZ knife holders support reusable knives for hard objects. Leica DB80 blades are validated for use.
• Sustainability and energy efficiency: uses refrigerant R290 (IPCC6 GWP: 0.02) and is engineered to reduce energy usage (up to 50% reduction versus previous models).
• Ergonomics: optimized working height, off-center microtome, armrest and knee-space design, adjustable footrest and compatibility with height-adjustable chairs to support long sectioning sessions.

Applications / Workflow advantages

• Clinical frozen sectioning with improved throughput and reduced environmental footprint.
• Spacious cryocabinet to store and organise tools, blades, freezing media and slides for an efficient workflow.

Characteristics / Technical specifications

• Chamber temperature range: -5°C to -35°C (adjustable in 1 K increments)
• Chamber cool down time from ambient: < 2 h (230V/50Hz and 120V/60Hz versions)
• Specimen head temperature range: -10°C to -50°C
• Freezing shelf lowest temperature: -42°C (at chamber temp. -35°C)
• Quickfreeze stations temperature: -59°C (at chamber temp. -35°C)
• Number of freezing stations: 15 + 2 quick freeze stations
• Refrigerant type: R290 (IPCC6 GWP: 0.02)
• Section thickness range: 1 to 100 µm
• Trimming thickness range: 10 to 40 µm (clinical mode); 1 to 600 µm (research mode)
• Electronic coarse feed: Single: 20 µm; Slow: 300 µm/s; Fast: 900 µm/s
• Vertical stroke: 59 mm
• Specimen retraction: 20 µm (can be switched off)
• Maximum specimen size (WxHxD): 80 x 50 x 25 mm
• Overall size (W x D x H): 700 x 850 x 1215 mm (without handwheel); 835 x 850 x 1215 mm (with handwheel)
• Working height: 1025 mm (armrest); 900 mm (handwheel)
• Weight: Max. 172 kg with accessories