Electric microtome cryostat CM3050 S

for researchCryosectioningfor neurology

Product overview
The Leica CM3050 S cryostat is a clinical/research cryosectioning instrument designed to support long serial sectioning tasks with enhanced ergonomics, reproducibility and workflow efficiency. It combines a motorized microtome drive, precise specimen orientation and dedicated cooling for demanding histology and neuroscience applications.

Key features
Precision sectioning
Precise specimen orientation with a zero position allows x/y adjustment up to 8°. The horizontal specimen feed of 25 mm and controlled specimen retraction permit reproducible thin sections across large or delicate samples.

Precision cooling
An independent refrigeration circuit for the object head provides targeted temperature control for challenging specimens (e.g., brain or fatty tissue). High-efficiency insulation and a dedicated chamber cooling maintain stable cryochamber temperatures for extended serial cutting sessions.

Stay organized
A large cryochamber with freezing stage and tool tray, plus an easily accessible storage area on top of the unit, keeps instruments and consumables at hand. The motor drive with foot pedal enables hands-free operation during sample handling.

Stay focused
Section thickness totalizer and counter with reset and reverse-counter functions simplify target preparation and trimming between levels, supporting reproducible workflows and batch processing.

Comfortable working position
The low working height with knee space allows comfortable seated operation; an optional electrohydraulic height adjustment raises the instrument for standing work when required.

Technical specifications

• Model: Leica CM3050 S Cryostat
• Width: 882 mm
• Depth: 766 mm
• Height: 1040 mm
• Weight (incl. microtome): approx. 180 kg
• Cryochamber temperature setting range: 0 °C to -40 °C
• Object/freezing shelf cooling range: approx. -43 °C freezing shelf temp at 22 °C ambient; alternative range -10 °C to -50 °C (±3 K)
• Maximum specimen size: 40 x 55 mm
• Horizontal specimen feed: 25 mm; vertical stroke: 59 mm; specimen retraction: 50 µm
• Specimen precision orientation: up to ±8° (x/y/z axis)
• Section thickness setting: 0.5 to 300 µm; trimming: 5 to 150 µm ±0.5 µm in steps of 5, 10, 30, 50, 100, 150 µm
• Cutting speed ranges: 0.1–170 mm/s and 0.1–100 mm/s; Vmax 210 mm/s
• Motorized coarse feed speeds: 500 µm/s and 1,000 µm/s
• Section counter and thickness totalizer with reverse counter and reset
• Defrosting: programmable (1 automatic defrost cycle per 24 h; duration 6–12 min) and manual defrost
• Freezing shelf temperature: approx. -43 °C at ambient 22 °C
• Dimensions (W x H x D): 882 x 1040 x 766 mm
• Power draw: 1800 VA