Solution reagent kit respiraScreen 1
diagnosticRT-qPCRliquid

solution reagent kit
solution reagent kit
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Characteristics

Type
solution
Applications
diagnostic, RT-qPCR
Format
liquid
Tested parameter
for genes
Micro-organism
SARS-COV-2, influenza A, respiratory syncytial virus, influenza B
Method
enzymatic
Storage temperature

-18 °C
(-0 °F)

Description

For the simultaneous in vitro detection and differentiation of RNA of Influenza Virus (Flu A and Flu B), Respiratory Syncytial Virus (RSV A and RSV B) and SARSCoV-2 (E gene and RdRP gene), extracted from biological specimens. 1 Intended Use The respiraScreen 1 real time RT-PCR Kit is a screening assay for the simultaneous detection of three groups of different respiratory viruses. The design allows the differentiation of Influenza Virus (Flu A, Flu B) and Respiratory Syncytial Virus (RSV A, RSV B) from the pandemic coronavirus SARS-CoV-2 (E gene and RdRP gene), extracted from biological specimens. 2 Pathogen Information Influenza Viruses belong to the family of Orthomyxoviridae and are the causative agent of ‘the flu’. Influenza A and B viruses have a single stranded RNA genome, consisting of 8 RNA segments. The genome of Influenza A Viruses is characterized by a high mutation frequency, the so-called ‘antigenic drift‘. Numerous subtypes of Influenza A Viruses are known. They can be categorized by their surface antigens H (haemagglutinin) and N (neuraminidase): Influenza A (H1N1) Virus, Influenza A (H5N1) Virus etc. Therefore, yearly in silico analysis of the sequences of newly emerged subtypes is done, to prevent false negative results caused by primer and/or probe mismatches. Influenza B viruses show a 2 – 3 times slower mutation rate then type A. Respiratory Syncytial Viruses are enveloped negative-sense, single stranded RNA Viruses of the Pneumoviridae family, genus Orthopneumovirus. RSV are divided into subgroups A and B. RSV is a virus that causes infections of the lungs and respiratory tract.

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MEDICA 2024
MEDICA 2024

11-14 Nov 2024 Düsseldorf (Germany) Hall 3 - Stand D62

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