Rapid gastrointestinal disease test 501040

for antigensbacteriaHelicobacter pylori

Benefits Accurate 98.5% sensitivity, 98.1% specificity compared with endoscopy. Rapid Results come out in 15 minutes. Non-invasive and non-radioactive Room temperature storage Specifications Sensitivity 98.5% Specificity 98.1% Accuracy 98.3% CE marked Kit Size=20 tests File: Manuals/MSDS INTRODUCTION Helicobacter pylori (also known as Campylobacter pylori) is a spiral-shaped gram negative bacteria which infects the gastric mucosa. H. pylori causes several gastro-enteric diseases such as non-ulcerous dyspepsia, gastric and duodenal ulcer, active gastritis and can even increase the risk of stomach adenocarcinoma. Many H. pylori strains have been isolated. Among them, the strain expressing CagA antigen is strongly immunogenic and is of utmost clinical importance. Literature articles report that in infected patients producing antibodies against CagA, the risk of gastric cancer is up to five times higher than reference groups infected with CagA negative bacteria. Other associated antigens such as CagII and CagC seems to act as starting agents of sudden inflammatory responses which can provoke ulceration (peptic ulcer), allergic episodes, and decrease of therapy efficacy.