Optical microscope N-SIM S

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Doubling the conventional resolution limit for live cell time-lapse imaging. The N-SIM S Super Resolution Microscope is a unique high-speed structured illumination system that achieves acquisition speeds of up to 15 fps, enabling fast biological processes to be captured at twice the spatial resolution of conventional light microscopes (up to 115nm in XY). Combining the N-SIM S and a confocal microscope gives you the flexibility to select a location in the confocal image and switch to super-resolution to view the desired part of the location in minute detail. High-speed super-resolution imaging at 15 fps Nikon’s new high-speed structured illumination system utilizes a novel pattern modulation technology to generate fast and precise switching of illumination patterns. The N-SIM S achieves incredible acquisition speeds (up to 15 fps*), enabling super-resolution time-lapse imaging of live cells and intracellular dynamics. Live-cell imaging at double the resolution of conventional light microscopes The N-SIM S utilizes Nikon's innovative approach to Structured Illumination Microscopy technology. By pairing this powerful technology with Nikon’s renowned objectives, which achieve an unparalleled numerical aperture of 1.49, the N-SIM S nearly doubles (to approximately 115 nm*) the spatial resolution of conventional light microscopes, enabling detailed visualization of minute intracellular structures and their interactions. * This value is the FWHM measurement of 100 nm beads excited with a 488 nm laser in 3D-SIM mode. In TIRF-SIM mode, 86 nm is achieved using 40 nm beads excited with a 488 nm laser.