Allograft bone substitute BioReady® DBM

for orthopedic surgeryputty

BioReady® DBM Putty and Putty with Chips BioReady® DBM Putty and Putty with Chips is an extension of RTI Surgical’s demineralized bone matrix (DBM) portfolio. This ready-to-use DBM implant provides convenience, excellent robust handling, verified osteoinductive* (OI) potential and sterility. BioReady DBM Putty and Putty with Chips are 100 percent allograft, and each donor lot is tested for osteoinductive potential. Data shows that BioReady DBM retains its osteoinductive potential throughout its entire shelf life.1 This ready-to-use implant does not require any preparation, such as thawing or mixing, and it is available in various sizes for use as a bone void filler in many types of surgical procedures. *DBM or representative finished implant is either assayed in vivo in the modified athymic nude rat for bone formation or in vitro for endogenous BMP-2 as a surrogate test marker for osteoinductive potential. Because the combination of various proteins is responsible for osteoinductive potential, when assayed in vitro, DBM is also screened for the presence of BMP-7. Findings from an in vitro assay or animal model are not necessarily predictive of human clinical results. 1Osteoinductivity of BioReady® DBM Putty in Athymic Rat Model. Steven T. Moore, Rasa Zhukauskas, and Ronald R. Cobb. Features & Benefits Ready-to-use 100% allograft Pliable without becoming hard or setting Carrier processed from DBM Retains OI potential throughout entire shelf life Labeled sterile Putty: 56% DBM by weight Putty with chips: 42% DBM by weight rilization Cancelle® SP DBM Sterilization Process