Product integrity and easy validation thanks to precise, reproducible capping and sealing processes
Low-particle processes and hygienic design support Annex 1 compliance and minimize contamination risks
Integrated coding and verification enable full traceability and regulatory compliance
Multiple inspection systems maximize product yield
Scalable solutions and lifecycle services ensure reliable, future-ready fill-finish operations
It is the crucial final step in pharmaceutical fill-finish processes: Vials and infusion bottles must be securely capped and sealed to maintain sterility and ensure the quality of sensitive products throughout the supply chain. Pharmaceutical and biotech companies face the challenge of combining precise, reproducible processes with low-particle operation under strict regulatory requirements such as Annex 1.
At the same time, increasing product diversity and batch variability require flexible equipment that can handle different container and cap formats without compromising efficiency. Syntegon’s portfolio of capping, sealing, and coding machines supports pharmaceutical and biotech companies in addressing these demands.
Our ARF-B and VRK overseal capping machines deliver the reproducible precision, validatable compliance, and flexible efficiency required in modern fill-finish environments.
The ARF-B caps and seals up to 8,400 containers per hour and is designed for maximum product and operator safety: With its low-particle crimping method and transport system that releases containers during the crimping process, it ensures ideal isolator use and full Annex 1 compliance.