Automated sample preparation system Transcend VTLX-1

for sample preparationfor liquid chromatographyfor chromatography

Product overview
The Thermo Scientific Transcend TLX systems with TurboFlow technology provide automated online sample cleanup for complex matrices to improve LC‑MS detection, reduce manual sample preparation and increase laboratory throughput. The TurboFlow approach combines chromatographic mechanisms to remove interferences prior to HPLC/UHPLC separation and mass spectrometry analysis.

Function and benefits
TurboFlow integrates diffusion, chemistry and size‑exclusion principles to perform selective online cleanup of dirty or challenging matrices before LC‑MS analysis. Key advantages include:

• Minimised manual sample preparation and direct injection workflows for plasma, urine, food and other complex matrices.
• Reduced ion suppression and improved detection specificity through online cleanup.
• Shorter hands‑on time by simplifying multi‑step sample preparation protocols.
• Method standardisation across different matrices, easing method transfer and development.

Software and compatibility
ARIA control software manages pump operation, valve switching, cleaning and gradients to optimise performance and productivity on Transcend systems. Transcend TLX systems are compatible with Xcalibur and TraceFinder mass spectrometry software and feature an intuitive graphical user interface to facilitate TurboFlow method deployment.

Available models

• 60500-60301-02 | Transcend VTLX-1 System | 1 LC channel
• 60500-60202-02 | Transcend TLX-2 System | 2 LC channels
• 60500-60203-02 | Transcend TLX-4 System | 4 LC channels

Technical specifications

• Autosampler: Vanquish Dual Split Sampler FT
• LC channels: 1–4 (depending on model)
• Pumps: Vanquish Quaternary Pump F and Vanquish Binary Pump F combinations
• Unit size: per unit

Ordering & availability

• Spare/part reference: 60500-60203 (verify exact part/model when ordering).
• Current availability: contact Thermo Scientific or authorised distributors for up‑to‑date stock information and compatible alternatives.
• When requesting support or quotes, provide the catalog number(s) and target matrix to ensure compatibility.