OverviewThe Pannoramic 75 is a high-throughput digital slide scanner designed for brightfield and fluorescence whole‑slide imaging in research and clinical laboratories. It supports dual-mode scanning with automatic loading for 75 slides, continuous operation and integration into digital pathology workflows.
SummaryBuilt around a continuously moving stage and advanced Plan‑Apochromat optics, the system pairs a 5 MP brightfield color camera (72 fps) with a back‑illuminated 16‑bit 4.2 MP sCMOS fluorescence camera. Optional 10× fluorescence objective and motorized objective/camera changers enable rapid transitions and high sensitivity imaging. Automation features include server‑side barcode reading, automated tissue and coverslip detection, and software tools for image management and analysis.
Key Features- 75‑slide capacity (3 magazines of 25 slides) with automatic loading and continuous scanning to maximize throughput.
- Dual‑mode imaging: brightfield and fluorescence with area scanning and software autofocus.
- High‑quality brightfield imaging from a dedicated 5 MP color CMOS camera (72 fps) for accurate color and sharpness.
- Accelerated fluorescence scanning with an optional 10× fluorescence objective for faster multiplexed acquisitions.
- Back‑illuminated 16‑bit 4.2 MP sCMOS fluorescence camera for high sensitivity at low signal intensities.
- 9‑position motorized fluorescence filter changer with multiband filter support for flexible channel configurations.
- Motorized objective and camera changers for automated BF/FL transitions and multi‑objective workflows.
- Automated tissue and coverslip detection plus server‑side barcode reading for robust sample tracking.
- Integration with Pannoramic Scanner Software, SlideViewer, SlideManager, Quant and third‑party analysis/management tools.
Scan Examples / Imaging OutputProduces publication‑quality images in MRXS native format with export options to JPG, JPEGXR, BMP, PNG, TIFF, Roche TIFF, SVS and DICOM. Supports area scanning, software flat‑field correction, deconvolution, optional Z‑stack (1–30 layers, 0.2–2 µm spacing) and extended focus imaging.
Applications / Use CasesSuited for research and diagnostic workflows including cancer research, genetics, cytopathology, biopsy diagnostics, biomedical research, and pathology services in hospitals and research institutes. Configurable for both low‑volume and high‑throughput laboratory environments.
Technical specifications- Capacity: 75 slides (3 magazines of 25 slides) with automatic loading and continuous scanning.
- Scanning modes: Brightfield and Fluorescence (dual‑mode).
- Brightfield camera: 5 MP color CMOS, 72 fps.
- Fluorescence camera: Back‑illuminated 16‑bit 4.2 MP sCMOS.
- Objectives (available): Plan‑Apochromat 10×/0.3 NA (fluorescence option), 20×/0.8 NA (default), 40×/0.95 NA (optional). Brightfield magnification up to 103×; fluorescence up to 98× with 1.6× adapter.
- Resolution: down to 0.10 µm/pixel (with 40× objective; fluorescence down to 0.10 µm/pixel with 40× + 1.6× adapter).
- Brightfield speed: ~1 min 30 s for 15 × 15 mm at 0.19 µm/pixel.
- Fluorescence speed: ~8 min 30 s for 15 × 15 mm with 3 channels at 20 ms exposure (typical).
- Fluorescence optics: Optional 10× fluorescence objective; 9‑position motorized filter changer; multiband light engine options (Lumencor SOLA, Spectra III, CoolLED pE‑800) covering ~380–740 nm.
- Illumination (brightfield): LED transmitted light with 3DHISTECH LED FLASH technology (avg. lifetime ~60,000 hours).
- Autofocus & detection: Fast multicolor fluorescence pre‑scan, software autofocus, flat‑field correction, deconvolution; USB preview camera for tissue/coverslip detection.
- Z‑stack: Optional 1–30 layers, adjustable spacing 0.2–2 µm.
- Barcode reading: 1D and 2D (Code39, Code128, QR, Data Matrix).
- Slide compatibility: 75.0–76.2 mm (L) × 25.0–26.0 mm (W) × 0.9–1.2 mm (T); coverslips No.1 or 1.5 (0.13–0.19 mm).
- Image formats: MRXS native; export to JPG, JPEGXR, BMP, PNG, TIFF, Roche TIFF, SVS, DICOM.
- Dimensions (scanner): approx. 673 × 689 × 546 mm.
- Weight (scanner): approx. 49 kg.
- Options: Motorized objective changer (dual‑objective config.), Z‑stack/multilayer scanning, extended focus, motorized camera changer for BF/FL switching.