syphilis assay kit / IgG / IgM / Treponema pallidum
81100, 81051 - 81051/12
IgG, IgM, Treponema pallidum
The serological diagnosis of syphilis is performed by demonstrating the presence of significant levels of specific Treponema pallidum (TP) antibodies in the serum sample. The reference method used is the FTA-ABS technique but its execution is laborious and the interpretation of the results is not simple; alternative methods have therefore been introduced to simplify the procedure. The TPHA test is the preferred technique for screening purposes, in as far as it detects specific Ig even at low titers. Unfortunately, the result of the test is determined by subjective interpretation as the test cannot be completely automated. The TPHA test is not sensitive in the primary phase. The kits allows screening with the ELISA method. It reveals the presence of specific antibodies of any class, and can be completely automated. The specific assay of IgM as opposed to IgG is of particular importance in the diagnosis of congenital Syphilis.