Encephalitis assay kit 81276
virusserumELISA

encephalitis assay kit
encephalitis assay kit
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Characteristics

Applications
for encephalitis
Micro-organism
virus
Sample type
serum
Analysis mode
ELISA
Result display time

70 min

Specificity

96.6 %

Sensitivity

94.4 %

Description

Tick-borne encephalitis (TBE) is a viral infectious disease, which affects Central Nervous System, caused by an arbovirus from the family Flaviviridae. Reservoir hosts of the virus are forest animals and the transmission, to humans and animals, occurs through tick bites or, exceptionally, by consumption of infected heat untreated milk. Up to 70% of infections are clinically inapparent or with mild symptoms; in the remaining 30% of cases, after an incubation period of 3-14 days, nonspecific flu-like symptoms occur. After some days of remission, the second phase of the disease develops. This phase is characterized by aggravated headaches, ophtalmoplegia, vomiting, malaise, meningeal symptoms, cranial nerve paralysis and paresis of the limbs. An acute stage of tick-borne encephalitis lasts 1 to 3 weeks. More severe course of the disease, often with lasting ill effects, can be observed in senior patients. The diagnosis is based on anamnesis, clinical picture and results of laboratory tests such as the detection of specific IgM and IgG antibodies. The IgG antibodies protect the organism against a new infection and they can be detected over a long period (several years) after the past infection or vaccination. The IgM antibodies are serological markers of acute infection and their production can last up to 10 months. Method Immunoenzymatic method for the qualitative determination of IgG and IgM-class antibodies to Tick-borne Encephalitis Virus in human serum, using a disposable device applied on the Chorus and Chorus TRIO instruments.

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