Parvovirus assay kit 81150
serumELISA

parvovirus assay kit
parvovirus assay kit
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Characteristics

Micro-organism
parvovirus
Sample type
serum
Analysis mode
ELISA
Result display time

40 min

Specificity

99.7 %

Sensitivity

99.3 %

Description

Parvovirus B19 is the smallest known virus; it was discovered in the blood of donors in 1974 and up to now three different genotypes were identified. It has a high stability against environmental factors and detergents. Parvovirus B19 infections are present in all the world, especially during spring; epidemic attacks can occur in kindergartens and schools. The virus is transmitted by aerosol, through the blood or its derivatives or through the placenta; the incubation period is between 4 and 14 days and it can be detected in infected patients’ serum between the third and the sixteenth day after infection. In healthy adults the detection of antibodies gives positive results in about 70% of cases. Acute infections are more frequent between 6 and 15 years old. In children, the virus causes the fifth disease. When the rash appears, the patient is no longer infectious. In some cases arthritic manifestations with arthralgia can appear. The virus replicates in the erythroblasts causing temporary anemia; the infection can lead to complications in immunocompromised patients. Infection during pregnancy can cause inhibition of erythropoiesis in the fetus resulting in anemia and fetal hydrops even until death. The determination of anti-Parvovirus B19 antibodies by ELISA technique is the standard method for the diagnosis of Parvovirus infections: IgM are detected up to 3-5 months from infection while IgG appear by the third week of infection and persist for the life. Method Immunoenzymatic method for the qualitative determination of IgG and IgM-class antibodies to Parvovirus B19 in human serum, using a disposable device applied on the Chorus and Chorus TRIO instruments.

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