EliGene® Mycoplasma hom/gen UNI is intended for DNA diagnostics of pathogenic species Mycoplasma hominis and Mycoplasma genitalium from isolated DNA sample.
Principle of the method
This diagnostic kit is based on RealTime PCR method using Molecular Beacons hybridization probes. In this kit for the detection of Mycoplasma hominis and genitalium DNA and internal control primers and Molecular Beacons labeled probes (FAM and HEX) are used.
Mycoplasma is bacterium belonging to the family Mycoplasmataceae which is comprised of group of microorganisms that cause respiratory and genital tract infection. These bacteria are detected in about 70% of sexually active people.
Mycoplasma hominis is associated with inflammatory diseases in a pelvis region, bacterial vaginitis, post-natal fever, sepsis and infections of central nerve system with serious consequences. This bacterium is also presumed to play a role during the development of woman infertility even if a literature and studies are not homogenous.
Mycoplasma genitalium is the main cause of non-Chlamydial and non-gonococcal urethritis (NCNGU) in men and cervicitis in women. M. genitalium bacteria infections have been associated also with inflammatory diseases in a pelvis region but this role has not been confirmed.