Radiotracer synthesis platform NEPTIS® LC

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Overview
The modular platform for therapeutic agents. Run a broad portfolio across diagnostics and therapy on a single LC platform with guided sequences for consistent day-to-day operation.

Supported isotopes

• 68Ga
• 188Re
• 177Lu
• 89Zr
• 90Y
• 131I
• 225Ac
• 99mTc

Key benefits & features

• One platform, many isotopes — supports synthesis of diagnostic and therapeutic tracers with guided sequences for reproducible operation.
• Compact without compromise — up to three LC modules fit in a single hot cell (mini‑cell) while preserving versatility, fluid pathway flexibility and tracer‑switching.
• Proven — supports labelling of small molecules, nanobodies and nanoparticles across a wide range of isotopes and workflows.
• Modular — sensors can be installed on the cassette for fully automated purification; custom modules can be designed for specific workflows.
• HPLC‑ready — can be paired with NEPTIS® SP for HPLC purification with fully integrated control so injection and reformulation run as one guided sequence.
• Reliable — patented WNE® 3‑position pneumatic actuators control in‑cell motion; CPU located outside hot cell for fewer failure points and increased uptime.

Accessories & capabilities

• Actuators: 3 ramps × 5 pneumatic (3‑position) actuators (WNE® system).
• Detectors: 3 radioactivity detectors (plus 1 optional).
• Syringe driver: 1 (10 mL).
• Heating & reactor ovens: 1 (plus 1 optional).
• Sensors available: vacuum, flow and pressure sensing for process control.
• Software: Browser‑based NEPTIS® Control with Designer and Trending for method development and run analytics.

Applications
Platform supports synthesis of new labelled compounds including small molecules, nanobodies and nanoparticles; suitable as a flexible base for R&D and clinical radiochemistry workflows.

Technical specifications

• Commercial name: NEPTIS® LC
• Actuators: 3 ramps × 5 pneumatic (3‑position) actuators (WNE® system)
• Hot cell compatibility: Up to 3 LC modules in one mini‑cell
• Detectors: 3 radioactivity detectors (+1 optional)
• Dimensions (w × d × h): 280 × 240 × 400 mm / 11.0 × 9.4 × 15.7 in
• Syringe drivers: 1 (10 mL)
• Weight: 20 kg / 44 lbs
• Heating & Reactor ovens: 1 (+1 optional)
• Ready‑to‑use cassettes available: No
• Sensors: Vacuum, flow and pressure
• Software: Browser‑based NEPTIS® Control with Designer and Trending for method development and run analytics