Research granulator ROTO CUBE

for research and developmentlaboratoryfor production

Overview
ROTO CUBE is a single-pot granulation system enabling in-containment processing from loading raw powders to discharge of dry milled granules in a single, completely sealed bowl. It ensures dust-free processing and eliminates contact between product, operator and environment. Key process features include accurate wet granulation end-point detection, tilting bowl and GA.ST. gas stripping during vacuum drying for efficient drying and high-quality granules.

Machine overview
All-in-one bowl solution for granulation suitable for high-containment processes; designed to maximise product yield while minimising product transfers and cleaning effort. Particularly suitable for HAPI granulation due to compact design and working principles.

Highlights

• Safety in containment: suitable for high-containment processes; product transfers and surfaces in contact with the product are significantly reduced.
• Safe processing: dust-free operation, safe use of solvents and reduced risk of contamination.
• Enhanced tilting: tilting bowl increases surface available for heat exchange and avoids product sticking, shortening drying time.
• Gas stripping (GA.ST.): inert gas injected through product mass to enhance vacuum drying efficiency.

Efficiency without compromise
Compact design and process features (reduced transfers, easier cleaning, optimised drying) maximise product yield and process efficiency for pharmaceutical applications.

Machine versions

• Lab Version: ROTOLAB — laboratory-scale single-pot processor for R&D, formulation and scale-up studies supporting technology transfer and meeting production requirements.

Gallery / Media
Includes machine imagery (bowl, lid, fibre and metallic filters, discharge) and an official machine video trailer.

Technical data (summary)
Model list and key operating ranges (table representation):
Model: 12 | 30 | 60 | 120 | 300 | 600 | 900 | 1,200 | 1,500
Recommended batch size range (l): 3-9 | 7-22 | 15-45 | 30-90 | 75-225 | 150-450 | 225-675 | 300-900 | 375-1,125
Product quantity (l): 4-8 | 10-20 | 20-40 | 40-80 | 100-200 | 200-400 | 300-600 | 400-800 | 500-1,000
Impeller speed (rpm): 20-597 | 20-434 | 20-347 | 10-277 | 10-205 | 10-163 | 10-142 | 10-130 | 10-122
Chopper speed (rpm): 700-1,500 (all models)

Machine dimensions (summary)
Dimensions A (mm): 1,400 | 1,450 | 2,200 | 2,360 | 2,900 | 3,100 | 3,500 | 3,500 | 4,300
B (mm): 2,020 (small sizes) up to 4,300 (largest sizes)
C (mm): 770 to 4,300 (varies by model)
D (mm): 2,610 to 4,860 (varies by model)
E (mm): 1,075 to 4,300 (varies by model)
F (mm): 1,400 to 4,300 (varies by model)
* Sizes over 1,500 litres available on request.

Notes

• Tilting bowl and GA.ST. (gas stripping) improve heat exchange and vacuum drying performance.
• Designed to minimise product handling and exposure for containment and HAPI processing.

Technical specifications

• Brand: IMA Active
• Product type: Single-pot granulation / all-in-one bowl processor
• Containment: High-containment capable; minimises product/operator/environment contact
• Process features: Wet granulation end-point detection, tilting bowl, vacuum drying with gas stripping (GA.ST.), chopper and impeller agitator
• Available models: 12, 30, 60, 120, 300, 600, 900, 1,200, 1,500 (and larger on request)
• Recommended batch size ranges (litres): see technical data table above
• Impeller speed range: ~10–597 rpm depending on model
• Chopper speed range: 700–1,500 rpm (all models)
• Typical uses: Pharmaceutical granulation including HAPI, R&D (ROTOLAB), scale-up and production
• Key benefits: Dust-free processing, reduced product transfers, improved drying efficiency, maximised yield