Research and development press PREXIMA THC

for highly potent active pharmaceutical ingredientsfor tabletspilot

Overview
PREXIMA THC is a tablet press designed for R&D applications, pilot batches and production support, also allowing the testing of HAPI. Conceived for total high-containment applications, PREXIMA THC ensures high flexibility and maximum reliability. Easily integrated with other equipment, it fits seamlessly into solid dose processing lines. Limited surfaces in contact with the product, sealed doors and negative pressure inside the processing area ensure operator and environmental safety. Access to the internal part of the machine is achieved via glove ports.

Key features

• High-containment design: sealed doors, negative pressure inside the processing area and glazed access via glove ports to protect operator and environment.
• Limited product-contact surfaces to reduce cross-contamination and simplify cleaning.
• Special turret configuration offering high flexibility: 8 stations (4B + 4D) allowing different die/tool arrangements.
• Straightforward scale-up: pre-compression and main compression forces similar to production machines to support reliable scale-up from R&D/pilot to production.
• Excellent accessibility for inspection, quick and thorough cleaning and straightforward operations.
• Smart control system: MAX corporate HMI to improve operator efficiency, responsiveness, predictability and ease of learning.
• Smart cleaning features: mobile spray gun inside the processing area and spray nozzle inside the hopper for preliminary wetting, followed by opening doors for final manual cleaning.

Processing & components (visual highlights)

• Die feeder
• Processing area
• Product sampling arrangement
• Glove port access
• Inflatable seal for containment
• Washing with glove port capability

Technical specifications

• Die type: B+D / D / B / BB
• Tool type (EU and TSM): B+D / D / B / B
• Number of press stations: 8 (4+4) (B+D) ; 13 (D) ; 16 (B) ; 19 (BB)
• Maximum tablet diameter (mm): 16-25 (B+D) ; 25 (D) ; 16 (B) ; 13 (BB)
• Maximum die filling (mm): 18
• Maximum output (tablets/hour): 20,400 (B+D) ; 66,300 (D) ; 81,600 (B) ; 96,900 (BB)
• Revolution per minute (min^-1): 10-85
• Maximum pre-compression force (kN): 10
• Maximum compaction force (kN): 60
• Maximum installed power (kW): 6.9
• Standard voltage: 400 V (+/- 10%) – 50Hz
• Pitch circle diameter (mm): 180