Orthopedic surgery bone cement PALACOS® R+G

Product overview
PALACOS® R+G is a high-viscosity, radiopaque polymethylmethacrylate (PMMA) bone cement containing the antibiotic gentamicin, coloured green (colourant E141). First introduced in 1972 as the first commercially produced antibiotic-loaded bone cement, it is widely used in arthroplasty and supported by registry data indicating lower revision rates and longer implant survival versus other bone cements.

Key features

• High-viscosity PMMA bone cement
• Radiopaque formulation
• Contains gentamicin antibiotic
• Green colouring (E141)

Indications

• Anchoring of endoprostheses in primary and revision arthroplasty of hip, knee, ankle, shoulder, elbow
• Bone reconstruction using the induced membrane technique after tumor surgery and/or trauma

Clinical evidence & history
PALACOS® R+G was launched in 1972 and is considered a reference product in arthroplasty. Real-world data from large arthroplasty registries (e.g., NJR) report significantly lower revision rates and longer implant survival for hip and knee implants cemented with PALACOS® R+G compared with other bone cements. Several comparative studies and registry analyses are cited in the literature.

Downloads
Relevant product documents and summary reports (e.g., NJR reports and presentations) are available as downloadable PDFs in the product documentation section.

Characteristics / Technical specifications

• Type: Antibiotic-loaded PMMA bone cement
• Viscosity: High-viscosity
• Antibiotic: Gentamicin incorporated
• Radiopacity: Radiopaque formulation
• Colour: Green (colourant E141)
• Primary indications: Prosthesis anchoring (hip, knee, ankle, shoulder, elbow); bone reconstruction via induced membrane technique
• Regulatory note: Indications and labelling may differ by region; refer to local instructions for use
• Manufacturer: Heraeus Medical