The Accel-Amplicon 56G Oncology Panel v2 offers comprehensive and hotspot coverage of 56 clinically-relevant oncology-related genes. This panel utilizes a 263-amplicon design, covering over 16,000 COSMIC mutations, to generate targeted libraries compatible with Illumina sequencing platforms and now includes 104 exonic and gender Sample_ID amplicons spiked in at a low percentage (2-4% of reads) for tracking tumor-normal pairs and samples in longitudinal studies.
The Accel-Amplicon 56G Oncology Panel v2 is compatible with short DNA fragments from both FFPE and cfDNA samples, and is well-suited for detection of clinically-relevant allele variants in DNA from circulating tumor cells (CTCs). This product is a complete kit that includes all components necessary for generating ready-to-sequence libraries, including primer pairs and indexed sequencing adapters.
Features:
Single-tube assay to interrogate 56G and Sample_ID targets
Ready-to-sequence libraries in 2 hours
Inputs as low as 10 ng
Limit of detection as low as 1%
Complete library generation in a single kit
Includes sample tracking primers
Benefits:
On-target specificity and coverage uniformity > 95%
Average amplicon size of 138 bp for compatibility with cfDNA and FFPE
Easily track samples within and between studies
Validate tumor/normal pairs and track samples throughout longitudinal studies
Compliment WGS or exome sequencing for sample tracking
Reduce sequencing cost with 384 indexing