Research test kit AMPLICON™ HS
oncologymolecularfor single cell DNA sequencing

research test kit
research test kit
Add to favorites
Compare this product


for research, oncology
Analysis mode
molecular, for single cell DNA sequencing
Other characteristics


Swift Amplicon HS Panels enable ultra-low frequency variant detection at and below 1% MAF from 10-20 ng of cell-free DNA (cfDNA) for Illumina® sequencers. Nucleotide errors, normally introduced during PCR and sequencing, are removed through the implementation of unique molecular identifiers (MIDs or UMIs) that uniquely label target templates during amplification. Highlights • Sensitive and Specific robustly detect SNVs and indels down to 0.25% allele frequency • Compatible with cfDNA and FFPE, amplifies from 10-50 ng of cfDNA • Fast workflow, high quality data From DNA to Illumina® compatible libraries within 3 hours • Paired Data Analysis Tools-Cloud-based or open source Swift Amplicon HS Panels enable variant calling at and below 1% frequency, with allele sensitivity dependent on the amount of input material available and the depth of sequencing. Using 10 ng of input DNA, this assay consistently detects variants at 0.5% with a recommended sequencing depth of at least 60,000x (1M reads) prior to deduplication with MIDs and 0.25% from 20 ng of input DNA. Swift Amplicon HS Panels facilitate targeted variant calling of clinically relevant mutations at and below 1% frequency. The technology enables this by the incorporation of molecular identifiers (MIDs or UMIs), which improve sensitivity and specificity by removing false positive errors introduced during PCR and sequencing. Supported Applications • Oncology – liquid biopsy cfDNA and FFPE tissue • Genome/Host Detection – Graft vs. Host Disease and Fetal in Maternal cfDNA* • Custom targets* Specifications Input DNA Required and Limit of Detection 10 ng for 0.5% detection; 20 ng for 0.25% detection


No catalogs are available for this product.

See all of Swift Biosciences‘s catalogs
*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.