Antibody IE7308

IgGfor clinical chemistryliquid

A correlation coefficient of r=1.00 was displayed when the Randox methodology was compared against commercially available methods. Excellent precision The Randox IgE assay displayed a precision < 4.0% CV. Excellent measuring range The Randox IgE assay has a measuring range of 25 – 1000 IU/ml for the comfortable detection of clinically important results. Liquid ready-to-use The Randox IgE assay is available in a liquid ready-to-use format for convenience and ease-of-use. Calibrator and controls available Dedicated IgE calibrator and specific protein controls available for a complete testing package. Applications available Applications available detailing instrument-specific settings for the convenient use of the Randox IgE assay on a variety of clinical chemistry analysers. Immunoglobulin E (IgE) is one of five classes of immunoglobulins (IgA, IgD, IgE, IgG and IgM). IgE was the last immunoglobulin to be discovered. However, since it’s discovery, vast amounts of research have been aimed at characterising its physiological and clinical significance’s. Whilst IgEs chemical structure is unique compared to the rest of the immunoglobulin family (lacks a ‘hinge’ region in the centre of the molecule and gets replaced by the C-epsilon2 domain), it has an array of physiological functions. For immunoglobulin E to fulfil its function, the Fc portion of the antibody must bind to a given cellular receptor located on certain cell types, such as eosinophil or mast cells. Whilst many an array of cellular receptors have been identified, the main ones are Fc-epsilon-RI, Fc-epsilon-II and CD23.