Solution reagent 562 series

for clinical chemistryliquid

The clearance method produces results in as little as ten minutes, facilitating faster patient diagnosis and treatment plan implementation. The previous methods, ultracentrifugation and electrophoresis, were laborious and time consuming. Exceptional correlation A correlation coefficient of r=0.91 was displayed when the Randox methodology was compared against the gold standard method, ultracentrifugation. Liquid ready-to-use assay The Randox sdLDL-C assay is available in a liquid ready-to-use format for convenience and ease-of-use. Calibrator & Controls Dedicated calibrator and control available Dedicated sdLDL-C calibrator and control available offering a complete testing package. Applications available Applications are available detailing instrument-specific settings for the convenient use of the Randox sdLDL-C assay on a wide range of clinical chemistry analysers. Diagnostic Uses Physiological Significance When measuring LDL cholesterol (LDL-C), it is the cholesterol mass within the LDL particles that is being measured. The LDL particle population within LDL is heterogeneous – meaning that the size, density & composition of each particle will be different. sdLDL-C is a subfraction of low density lipoprotein (LDL) with smaller particle size and higher density than larger more buoyant LDL. They all transport triglycerides and cholesterol to the tissues, but their atherogenesis varies according to their size. sdLDL-C will more readily permeate the inner arterial wall. sdLDL-C is more susceptible to oxidation and has a lower affinity to the hepatic LDL receptor, and as such circulates in the blood longer 1.