Solution reagent CR series

for clinical chemistryliquidcreatinine

The Randox Jaffe creatinine assay displayed a within run precision of < 4.0% CV. Exceptional correlation The Randox Jaffe creatinine assay displayed a correlation coefficient of at least r=0.99 when compared to commercially available methods. Liquid ready-to-use The Randox Jaffe creatinine assay is available in a liquid ready-to-use format for convenience and ease-of-use. Calibrator and controls available Calibrator and controls available offering a complete testing package. Applications available Applications available detailing instrument-specific settings for the convenient use of the Randox Jaffe creatinine assay on a variety of clinical chemistry analysers. More useful information Physiological Significance Creatinine is the end-product of muscle catabolism of creatine. In humans, creatinine production is relatively stable, but mainly depends on muscles mass. Consequently, any physiological changes in muscle mass will cause a variation in the creatinine pool independently of GFR changes. Creatinine is freely filtered by the glomerulus at a constant rate with 10% to 40% secreted by the tubules 1 Renal Function According to the National Institutes of health, the overall prevalence of chronic kidney disease (CKD) is approximately 14% 2. Creatinine is the most commonly utilised assay in the assessment of renal function 3. The National Kidney Disease Education Program recommends calculating GFR from SCr. Creatinine measurements are useful in the monitoring of disease progression, with the diagnosis of renal failure when SCr levels are greater than the upper normal interval