The Randox Anti-Streptolysin O assay showed an excellent correlation coefficient of 0.97 compared against other commercially available methods.
Specificity
The antiserum of Randox Anti-Streptolysin O is monospecific for human ASO and has not been shown to cross react with other serum proteins.
Liquid ready-to-use
Available in a liquid ready-to-use format for convenience and ease-of-use.
Applications available
Applications available detailing instrument-specific settings for the convenient use of the Randox Anti-Streptolysin O assay on a variety of clinical chemistry analysers.
What is the Anti-Streptolysin O (ASO) assay used for?
What is Anti-Streptolysin O (ASO)?
Streptolysin O (SLO) is a toxic and lethal, exocellular immunogenic protein produced and released in response to Group A Streptococcal pyogenes. For more information on streptococcal infections, please click here [external link]. The release of SLO stimulates the production of Anti-Streptolysin O (ASO) antibodies to neutralise the SLO's haemolytic effects. The O in the name stands for oxygen-labile.
What is the Anti-Streptolysin O (ASO) assay used for?
The Anti-Streptolysin (ASO) test is used to determine recent streptococcal infection and post streptococcal complications which includes rheumatic fever and glomerulonephritis. The presence and level of ASO antibodies in human serum directly reflects the extent and degree of infection. Elevated levels of ASO may also be present in other conditions including scarlet fever, acute rheumatoid arthritis, tonsillitis and various other streptococcal infections as well as in health carriers.