Short-term absorbable suture thread Premisut PGAR

general surgeryoral surgeryophthalmic surgery

Overview
Premisut PGAR suture is a sterile, synthetic, multifilament braided fast-absorbable surgical suture manufactured from homopolymers of 100% glycolide. The polymer used has a lower molecular weight than standard Premisut PGA, resulting in a rapid absorption profile and accelerated loss of tensile strength after implantation. The suture is supplied undyed and is coated with a mixture of polycaprolactone and calcium stearate to improve handling, ensure smooth passage through tissue and facilitate knot tying.

Intended use / Indications
Premisut PGAR is intended for general soft tissue approximation where only short-term wound support is required and where a rapid absorbable profile is desirable. Typical indications include skin closure (including pediatric skin), episiotomy repair, circumcision, oral mucosa closure and conjunctival suturing in ophthalmic procedures.

Absorption and tissue reaction
After implantation, Premisut PGAR elicits a mild to moderate initial inflammatory response and is gradually replaced by ingrowth of fibrous connective tissue. Degradation occurs by hydrolysis of the polyglycolic acid polymer into glycolic acid, which is subsequently metabolized and eliminated by the body. This process produces an initial progressive loss of tensile strength followed by loss of suture mass.

Additional information
Technical characteristics (for example coating composition, tensile strength, needle type, sizes and packaging) may be adapted to meet specific market or clinical requirements.