Mid-term absorbable suture thread PREMISUT PDO

general surgeryophthalmic surgerypediatric cardiovascular surgery

Overview
PREMISUT PDO suture (Polydioxanone) is a sterile synthetic monofilament absorbable surgical suture manufactured from poly(p-dioxanone). Available dyed with D&C Violet No 2 or in undyed form. Designed to provide extended wound support where absorbable monofilament sutures are indicated.

Intended use
Intended for general soft tissue approximation, including paediatric cardiovascular tissue where growth is expected, and for ophthalmic procedures. Suitable when extended tensile support up to approximately six weeks is required.

Performance and absorption
Engineered to reduce variability in handling and tensile characteristics and to maintain wound support during the extended healing phase. After implantation it induces a minimal initial inflammatory response and is progressively replaced by fibrous connective tissue. PREMISUT PDO is hydrolyzed in tissues to monomers of 2-hydroxyethoxyacetic acid, which are absorbed and metabolized by the body. Absorption proceeds with a gradual loss of tensile strength followed by mass loss.

Notes
Technical features may be modified to meet market or clinical needs, for example:

• coating
• tensile strength
• needle type and composition
• sterile packaging

Technical characteristics / specifications

• Material: Polydioxanone (poly(p-dioxanone))
• Product type: Sterile synthetic monofilament absorbable surgical suture
• Colour: Dyed with D&C Violet No 2; undyed version available
• Intended applications: General soft tissue approximation; paediatric cardiovascular tissue with expected growth; ophthalmic surgery
• Extended wound support: Up to approximately six weeks
• Absorption mechanism: Hydrolysis to monomers of 2-hydroxyethoxyacetic acid; metabolized by the body
• Tissue reaction: Minimal initial inflammatory response; replaced by ingrowth of fibrous connective tissue
• Possible market variations: Coating, tensile strength, needle composition, packaging