Small animal operant behavior system LE870

passive avoidance

Presentation
The passive avoidance paradigm is a behavioural test used to inhibit an innate or learned tendency by pairing it with an aversive stimulus. It is widely used in pharmacology and neuroscience to evaluate memory, learning processes and the effects of treatments on fear-motivated behaviour. The LE870 design follows classical one-trial learning / two-compartment protocols derived from Kurtz & Pearl (1960) and Bures & Buresova (1963).

Operating principle
The test chamber consists of two compartments of contrasting size and illumination (large white compartment and small dark compartment). The primary measured variable is latency to enter the small compartment after training; experimental parameters such as the interval between aversive stimulation and retention test can be varied to assess short- and long-term memory.

Detection system
Animal position and zone entries are detected using high-sensitivity weight transducers with a measurement range of 10–800 g. This weight-based detection provides robust and precise zone-entry monitoring for small rodents and reduces false detections compared with photocell or grid-displacement systems.

Control and software options
BIOSEB Passive Avoidance boxes can be controlled via the LE2708 Programmer or the SHUTAVOID software. The LE2708 Programmer is recommended for single-box setups and can be linked to a PC using SEDACOM for RS232 data transfer (connection via a single cable; first box connected to PC by RS232 or USB). SHUTAVOID is suitable for simultaneous control of multiple boxes.

Documentation
A detailed PDF brochure with technical specifications, configuration options and recommended experimental protocols is available for this Passive Avoidance system.

Technical specifications

• Product name: Passive avoidance
• Reference: LE870
• Category: Learning/Memory - Attention - Addiction
• Detection method: high-sensitivity weight gauges (zone entry detection)
• Weight transducer measurement range: 10 to 800 grams
• Control options: LE2708 Programmer, SHUTAVOID software; optional SEDACOM for RS232 data transfer
• Typical applications: short-term and long-term memory assessment in small laboratory animals using fear-motivated paradigms