Xenograft bone substitute DEBONE

for maxillofacial surgeryfor orthopedic surgeryfor spine surgery

Overview
DEBONE is a collagen-based bone graft matrix developed for regenerative orthopedic, spinal and dental applications. It combines ultra-pure Type I bovine collagen with bioactive β-TCP to provide an osteoconductive, biocompatible and clinically versatile scaffold for bone defect repair.

Key composition
Ultra-pure Type I bovine collagen matrix (over 95% collagen purity) combined with β-TCP (beta-tricalcium phosphate) to promote mineralization, osteogenesis and gradual resorption with replacement by natural bone.

CE certification & ISO compliance
DEBONE is CE-certified and manufactured under a certified ISO Quality Management System, assuring sterility, traceability and quality control for implantable use.

Composition and osteogenic potential
The Type I bovine collagen serves as a natural extracellular matrix mimic supporting osteoblast attachment, vascular in-growth and cellular colonization. The incorporated β-TCP contributes to early mineralization, mechanical integrity and gradual resorption, forming an osteoconductive platform that facilitates biological bone regeneration.

Clinical advantages

• Bioabsorbable: naturally resorbs and is replaced by new bone, avoiding secondary removal procedures.
• Biocompatible and safe: low risk of immune reaction or inflammation.
• High osteoconductivity: supports cell adhesion, migration and proliferation.
• Available in two physical forms (granules and sponges) for surgical flexibility.
• Suitable across multiple surgical fields including orthopedics, dental, spine, maxillofacial and trauma.

Indications for use
DEBONE is intended for the repair of bone defects and voids including:

• Bone augmentation prior to implant placement
• Alveolar ridge reconstruction
• Sinus lift procedures
• Periodontal defect filling
• Long bone non-unions and fractures
• Cystic and tumor resection defects
• Spinal fusion and vertebral defect repair
• Trauma-related bone loss

Physical forms and particle sizes
DEBONE is manufactured in two physical forms to suit different defect types:

• Sponge (SW) — compressed and porous, shape-retaining, ideal for irregular cavities
• Granule (G) — loose particles for interspace filling and load adaptability

Available particle size ranges:

• 0.7–1.5 mm
• 2–3 mm
• 3–5 mm
• 6–7 mm

Product configurations (reference code — description)
DBN-0715W-5CC — Sponge, 5cc / 0.7–1.5 mm
DBN-23W-5CC — Sponge, 5cc / 2–3 mm
DBNG-5C-D03 — Granule, 5cc / 3–5 mm
DBNG-5C-D04 — Granule, 5cc / 6–7 mm
DBN-0715W-10CC — Sponge, 10cc / 0.7–1.5 mm
DBN-23W-10CC — Sponge, 10cc / 2–3 mm
DBNG-10C-D03 — Granule, 10cc / 3–5 mm
DBNG-10C-D04 — Granule, 10cc / 6–7 mm
DBN-0715W-15CC — Sponge, 15cc / 0.7–1.5 mm
DBN-23W-15CC — Sponge, 15cc / 2–3 mm
DBNG-15C-D03 — Granule, 15cc / 3–5 mm
DBNG-15C-D04 — Granule, 15cc / 6–7 mm
DBN-0715W-20CC — Sponge, 20cc / 0.7–1.5 mm
DBN-23W-20CC — Sponge, 20cc / 2–3 mm
DBNG-20C-D03 — Granule, 20cc / 3–5 mm
DBNG-20C-D04 — Granule, 20cc / 6–7 mm
DBN-0715W-30CC — Sponge, 30cc / 0.7–1.5 mm
DBN-23W-30CC — Sponge, 30cc / 2–3 mm
DBNG-30C-D03 — Granule, 30cc / 3–5 mm
DBNG-30C-D04 — Granule, 30cc / 6–7 mm

Packaging and sterility
All units are sterile-packaged, labeled with full traceability data, and ready for immediate surgical use.

Technical specifications

• Brand: Desu
• Commercial name (denomination): DEBONE
• Composition: Ultra-pure Type I bovine collagen matrix + β-TCP (beta-tricalcium phosphate)
• Collagen purity: >95%
• Physical forms: Sponge (SW) and Granule (G)
• Particle sizes: 0.7–1.5 mm, 2–3 mm, 3–5 mm, 6–7 mm
• Volume options: 5 cc, 10 cc, 15 cc, 20 cc, 30 cc
• Reference codes: see product configurations list above
• Sterility: sterile-packaged, labeled with traceability
• Regulatory: CE-certified; manufactured under certified ISO Quality Management System
• Clinical properties: bioabsorbable, biocompatible, osteoconductive, non-toxic, non-immunogenic