As the versatile synthetic sealant, surgeons rely on COSEAL Surgical Sealant as the only surgical sealant clinically proven to deliver both cardiovascular sealing and post-surgical adhesion prevention efficacy in cardiac and gynecological surgery.
3-in-1 Solution for Sealing and Adhesion Prevention
COSEAL is clinically proven to provide a rapid seal at vascular suture lines, as well as reduce air leaks occurring after lung resection as compared to standard surgical technique. Additionally, COSEAL reduces the severity of postoperative cardiac adhesions and gynecologic adhesions.
Mechanism of Action
COSEAL is composed of two synthetic biocompatible polyethylene glycol polymers that rapidly crosslink with proteins in tissue and mechanically adhere to synthetic graft material.
Additional Product Benefits
Flexible and Easy to Use
The translucent, motion-responsive material supports natural vascular dilation as well as conforms to the anatomy of the expanding and contracting lung.
Independent of the Coagulation Cascade
COSEAL works independent of the coagulation cascade, forming a direct mechanical barrier to blood flow regardless of the patient’s coagulation status.
Cost Savings and Fewer Complications
In a retrospective study of 102 aortic Bentall procedures, using COSEAL as a suture line reinforcement contributed to fewer complications with significant cost savings when compared to not using COSEAL.